The role of TAM family receptors in immune cell function: implications for cancer therapy
M Paolino, JM Penninger - Cancers, 2016 - mdpi.com
… Thus, modulation of TAM receptors has emerged as a potential … how TAM receptors control
immunity, with a particular focus on the regulation of anti-tumor responses and its implications …
immunity, with a particular focus on the regulation of anti-tumor responses and its implications …
Ligand activation of TAM family receptors-implications for tumor biology and therapeutic response
V Davra, SG Kimani, D Calianese, RB Birge - Cancers, 2016 - mdpi.com
… receptors, as well as novel strategies to target TAM ligands are being developed. This paper
will review the biology of TAM receptors … pursuit of TAM/Gas6 inhibitors in clinical practice. …
will review the biology of TAM receptors … pursuit of TAM/Gas6 inhibitors in clinical practice. …
The role of TAM family receptors and ligands in the nervous system: from development to pathobiology
… TAM receptors and their ligands in the nervous system. We highlight studies that explore the
function of TAM … , and multiple sclerosis (MS) using Gas6 −/− and TAM mutant mice models. …
function of TAM … , and multiple sclerosis (MS) using Gas6 −/− and TAM mutant mice models. …
Tam Receptor inhibition–implications for cancer and the immune system
P Aehnlich, RM Powell, MJW Peeters, A Rahbech… - Cancers, 2021 - mdpi.com
… interest and research into TAM inhibition. This … TAM receptor signaling in T cells and
natural killer (NK) cells. The aim of this review is to explore in detail the effects of TAM receptor …
natural killer (NK) cells. The aim of this review is to explore in detail the effects of TAM receptor …
Biology of the TAM receptors
G Lemke - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
The TAM receptors—Tyro3, Axl, and Mer—comprise a unique family of receptor tyrosine
kinases, in that as a group they play no essential role in embryonic development. Instead, they …
kinases, in that as a group they play no essential role in embryonic development. Instead, they …
TAM receptor tyrosine kinases: biologic functions, signaling, and potential therapeutic targeting in human cancer
RMA Linger, AK Keating, HS Earp… - Advances in cancer …, 2008 - Elsevier
… Further research will be necessary to evaluate the full clinical implications of TAM family …
The focus of this review is the TAM family which includes Tyro‐3, Axl, and Mer, three receptors …
The focus of this review is the TAM family which includes Tyro‐3, Axl, and Mer, three receptors …
Immunobiology of the TAM receptors
G Lemke, CV Rothlin - Nature Reviews Immunology, 2008 - nature.com
… Prospects and implications Recent insights into TAM receptor function have many implications
for our understanding of innate immune regulation and the treatment of immune system …
for our understanding of innate immune regulation and the treatment of immune system …
TAM receptor signaling in development
T Burstyn-Cohen - The International journal of developmental biology, 2017 - ijdb.ehu.es
… -receptor interactions may elicit different molecular and cellular responses. Many of the TAM
… This review highlights current knowledge on the role of TAM receptors and their ligands …
… This review highlights current knowledge on the role of TAM receptors and their ligands …
TAM receptors in leukemia: expression, signaling, and therapeutic implications
L Brandão, J Migdall-Wilson… - Critical Reviews™ in …, 2011 - dl.begellhouse.com
… This review summarizes the role of TAM receptors in leukemia. We outline TAM receptor …
delineate the signaling pathways downstream of receptor activation that have been implicated …
delineate the signaling pathways downstream of receptor activation that have been implicated …
TAM-ing T cells in the tumor microenvironment: implications for TAM receptor targeting
MJW Peeters, A Rahbech, P thor Straten - Cancer Immunology …, 2020 - Springer
… TAM receptors’ ambivalent functions on many different cell types therefore make therapeutic
… TAM receptors in the tumor microenvironment. We place particular focus on TAM receptors …
… TAM receptors in the tumor microenvironment. We place particular focus on TAM receptors …
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