Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution

X Xiao, CY Zhang, Z Zhang, Z Hu, M Li, T Li - Molecular Psychiatry, 2022 - nature.com
… In addition, many tandem repeats undergo tight natural … Taken together, the putative roles
of tandem repeats in the … to tandem repeats in the post-GWAS era of psychiatric disorders. …

Tandem repeats mediating genetic plasticity in health and disease

AJ Hannan - Nature Reviews Genetics, 2018 - nature.com
… Emerging genetic data also suggest roles for tandem repeat polymorphisms (TRPs) in
the … themes in tandem repeat biology, with a focus on the repeat-associated genetics and …

A new look at the challenging world of tandem repeats

V De Fonzo, E Bersani, F Aluffi-Pentini, V Parisi - Medical hypotheses, 2000 - Elsevier
… function the management of tandem repeats length; such a … tandem repeat managing
mechanisms ‘dynamical genetics’. … We shall collectively call such mechanisms ‘tandem repeat

Role of short tandem repeat DNA in forensic casework in the UK—past, present, and future perspectives

P Gill - Biotechniques, 2002 - Taylor & Francis
… The analysis of short tandem repeat (STR) DNA sequences is of fundamental importance
to forensic science because they have become the recognized standard in constructing …

A brief review of short tandem repeat mutation

H Fan, JY Chu - Genomics, Proteomics and Bioinformatics, 2007 - academic.oup.com
… Short tandem repeats (STRs) are short tandemly repeated DNA sequences that involve a
repetitive unit of 1–6 bp. Because of their polymorphisms and high mutation rates, STRs are …

Large-scale analysis of tandem repeat variability in the human genome

J Duitama, A Zablotskaya, R Gemayel… - Nucleic acids …, 2014 - academic.oup.com
tandem repeats of short (≤ 9bp) or long (> 9bp) repeated units, respectively (for a complete
list of terms used in this manuscript, see Supplementary Text S1). Tandem repeatsrepeated

Abundant contribution of short tandem repeats to gene expression variation in humans

M Gymrek, T Willems, A Guilmatre, H Zeng, B Markus… - … genetics, 2016 - nature.com
… We repeated the same analysis for genes with at least moderate (≥5%) cis heritability (… a
transcriptome-wide perspective on the role of STRs in gene expression (Fig. 2c). In this set of …

Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

OK Tørresen, B Star, P Mier… - Nucleic acids …, 2019 - academic.oup.com
… Here, we provide a review of the problems associated with tandem repeat sequences that …
hindered by a particularly high prevalence of tandem repeats. We complement this case study …

Mutation and selection processes regulating short tandem repeats give rise to genetic and phenotypic diversity across species

M Verbiest, M Maksimov, Y Jin… - Journal of …, 2023 - academic.oup.com
… , genes with tandem repeats in their regulatory regions exhibit greater gene expression
divergence between humans and other primates, underlining the contribution of these repeats in …

[图书][B] Tandem Repeats in Genes, Proteins, and Disease

DM Hatters, AJ Hannan - 2013 - Springer
… of tandem repeats in DNA, RNA, and protein, in healthy and diseased states. This will include
molecular genetics, … and cellular approaches to animal models of tandem repeat disorders. …