… contraceptives for men appears to be in our reach. In this article, we will highlight the potential
target events … The events being targeted are: 1) administration of hormones, herbal extracts…

… For example, only 70% of men achieved this target in 1 large male hormonal contraceptive
trial … In addition, the use of T could lead to disqualification from high-level sporting events. The …

… for almost one third of contraceptive use in the United States … 95%) for hormonally based
male contraceptives. Current barriers to … Nonhormonal methods, such as compounds that target …

… , an initial targeting of one junction … male infertility can be achieved by inducing junction
instability and defects in the testis, opening a new window of research for male contraceptive …

… target for male contraception. “Druggability,” from a pharmaceutical perspective, is critical to
success (ie, Is the target … with or abrogates key regulatory events associated with testicular …

… Research is continuing to identify other target areas for male contraceptive development, …
1970s in the USA and Europe in male contraceptive trials.These earlier studies showed that …

… on developing non-hormonal male contraceptive agents by targeting sperm formation and
maturation within … As a GPCR, it offers a drugable target for male contraceptive development. …

… Here we summarize landmark studies in male contraceptive development, showcase the …
are needed, and their results might help guide the field to target modes of delivery and dosage …

… These two observations indicated that Eppin is a potential target for the development of a
contraceptive and warranted fertility testing. As summarized in Table 3, the fertility study (O’…

… on sperm-specific targets for male contraception, focusing on those with … in male contraceptive
drug development targeting … events enabling the male gamete to fertilize the oocyte. Thus, …