… a pathway suggests that different extracellular signals can produce stimulus- and tissue-specific
responses by activating one or more MAPK pathways … downstream targets of p38 MAPK …

… Clinical studies targeting p38 MAPK in cancer Several clinical trials targeting p38 MAPK
in cancer are currently underway. Ralimetinib (LY2228820), for example, is a potent and …

… Therefore, miR-16, as a regulator of p38 MAPK, might be a diagnostic biomarker and a
target of PAs. In addition, based on miR-6-related studies, miR-6-protein and/or miR-6-lncRNA …

… and genotoxic stresses can activate p38 MAPK and JNK pathway. A number of representative
up and downstream targets are shown. Both p38 MAPK and JNK can mediate apoptosis …

… of MAPK activities. Given the promises of the drug inhibitors targeting the MAPK pathway
in inflammatory diseases, understanding the signaling mechanisms in MAPK regulation is not …

… of p38 regulation, targeting the TAB1-mediated non-canonical activation of p38 has a number
… Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide …

… Another study has linked the p38 MAPK pathway with inhibition of breast cancer metastasis
to bone by acting downstream of Kringle 1 domain of hepatocyte growth factor (HGFK1) and …

… In this study, the cellular target by which IFNα affects … engaged by IFNα, signals generated
by the p38 MAPK have been … of p38 MAPK pathway on IFNα-mediated effects on PV HPC. …

… In this review, we summarize recent advances in the targeting of p38 MAPK as a potential
strategy for the treatment of AD, focusing on the contributions of p38 MAPK pathways to AD …

… the ERK/MAPK pathway before they exert effects on target genes, hence, contributing to
pain responses in DRG neurons. The possible stimuli activating the ERK/MAPK pathway in …