Human skin: source of and target organ for angiotensin II

UM Steckelings, T Wollschläger, J Peters… - Experimental …, 2004 - Wiley Online Library
… study was to answer three major questions: Is human skin a target organ for Ang II; is Ang II
synthesized by human skin; and what could be a physiological role for Ang II in human skin? …

Human skin: an independent peripheral endocrine organ

CC Zouboulis - Hormone research, 2000 - karger.com
… The human skin is the target for a wide range of chemical messengers. These include several
hormones, which in the classical sense are defined as substances secreted into the blood …

Skin: major target organ of allergic reactions to small molecular weight compounds

HF Merk, JM Baron, MM Neis, DH Obrigkeit… - Toxicology and applied …, 2007 - Elsevier
Skin is a major target organ for allergic reactions to small … most frequent reason for occupational
skin diseases and the … were shown to be present in skin. Evidence supporting the role of …

The skin as target, vector, and effector organ in human immunodeficiency virus disease

A Blauvelt, SI Katz - Journal of investigative dermatology, 1995 - Elsevier
skin diseases have been studied extensively. However, the exact role that the skin plays as
a target, vector, and e1fector organ in HIV … studies on HIV and the skin, with an emphasis on …

The skin: target organ in immunotoxicology of small-molecular-weight compounds

HF Merk, B Sachs, J Baron - Skin Pharmacology and Physiology, 2001 - karger.com
… frequent skinskin is the principal target organ for a delayed-type immunological response;
this will be followed by drug-allergic reactions in which again the skin is a major target organ

The renaissance of human skin organ culture: a critical reappraisal

L Zhou, X Zhang, R Paus, Z Lu - Differentiation, 2018 - Elsevier
… ex vivo, such as the stable overexpression of selected genes targeted to well-defined
skin cell populations (for example, while the temporary overexpression of GFP in …

Human sympathetic outflows to skin and muscle target organs fluctuate concordantly over a wide range of time‐varying frequencies

A Bernjak, J Cui, S Iwase, T Mano… - The Journal of …, 2012 - Wiley Online Library
… Our findings treat the fundamental nature of human sympathetic rhythmicity: both skin and
muscle sympathetic outflows (which travel in different nerve fascicles to different target organs) …

The skin: an immunoreactive target organ during interleukin-2 administration

R Dummer, K Miller, C Eilles, G Burg - Dermatology, 1991 - karger.com
… The skin reactions associated with systemic IL-2 administration, show that the skin
actually participates as a target organ. They should be differentiated from drug erup tions. …

The skin as an endocrine organ

CC Zouboulis - Dermato-endocrinology, 2009 - Taylor & Francis
… Despite this knowledge, attention to the ability of human skin to fulfill … organ has only been
drawn lately.Citation2–Citation5 The human skin has been classically regarded as the target

Human organ rejuvenation by VEGF-A: Lessons from the skin

A Keren, M Bertolini, Y Keren, Y Ullmann, R Paus… - Science …, 2022 - science.org
target (2), dissecting the key drivers of human organ aging and developing effective
molecular strategies to prevent or even reverse it surely constitutes one of the most fundamental …