CRISPR-RT: a web application for designing CRISPR-C2c2 crRNA with improved target specificity

H Zhu, E Richmond, C Liang - Bioinformatics, 2018 - academic.oup.com
… Here we describe CRISPR-RT (CRISPR RNA-Targeting), the first web application to help
biologists design crRNAs with improved target specificity for the CRISPR-C2c2 system. …

[HTML][HTML] RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes

JF Lucier, LJ Bergeron, FP Brière, R Ouellette… - BMC …, 2006 - Springer
… Thus, the selection of a unique target sequence remains a … tool offers the specificity required
in order to target a unique mRNA … The commonly used Blast based target search is of limited …

Non-specificity of drug-target interactions–consequences for drug discovery

G Maggiora, V Gokhale - Frontiers in molecular design and …, 2016 - ACS Publications
… The dominant approach is still based on the single-target … While newer multi-target approaches
address some of the … lack of compound and target specificity that the growing amount of …

[HTML][HTML] OligoRAP–An Oligo Re-Annotation Pipeline to improve annotation and estimate target specificity

PBT Neerincx, H Rauwerda, H Nie, MAM Groenen… - BMC proceedings, 2009 - Springer
… annotation, but also oligo target specificity based on the amount and … target specificity oligos
are divided into six target specificity … is implemented as one or more web services [16], which …

Specificity-aware ontology generation for improving web service clustering

RAHM Rupasingha, I Paik… - IEICE TRANSACTIONS on …, 2018 - search.ieice.org
… a Web service clustering approach that uses novel ontology learning and a similarity calculation
method based on the specificity … to select a suitable target area of nodes. Expanding the …

Improving web service clustering through a novel ontology generation method by domain specificity

RAHM Rupasingha, I Paik… - … conference on web …, 2017 - ieeexplore.ieee.org
… With the exponential growth of Web applications, research related to Web service clustering
… hybrid specificity values. This procedure is outlined in Figure 4. According to the targeting

[HTML][HTML] BatchPrimer3: a high throughput web application for PCR and sequencing primer design

FM You, N Huo, YQ Gu, M Luo, Y Ma, D Hane… - BMC …, 2008 - Springer
… of each of AS primers to increase allelic specificity (See Table 1). … Because only one SNP is
taken as target and other SNPs … If multiple targets are set in one sequence, at least one target

[HTML][HTML] Cutoff Finder: a comprehensive and straightforward Web application enabling rapid biomarker cutoff optimization

J Budczies, F Klauschen, BV Sinn, B Győrffy… - PloS one, 2012 - journals.plos.org
… Here, the sum of sensitivity and specificity is maximized, equivalent to maximization of …
optimization of a target quantity in dependence of the cutoff. For example, the target quantity can …

Image specificity

M Jas, D Parikh - Proceedings of the IEEE Conference on …, 2015 - cv-foundation.org
… We call this the target image. The user inputs a query sentence q that describes the … realistic
applications (eg image search, that we explore later), it is practical to measure specificity by …

iSPOT: A web tool to infer the interaction specificity of families of protein modules

B Brannetti, M Helmer-Citterich - Nucleic acids research, 2003 - academic.oup.com
… motifs within their target proteins. The ability to infer the recognition specificity of such …
The SPOT procedure (10) has been developed to infer the recognition specificity of families …