VEGF-targeted therapy: therapeutic potential and recent advances

LS Rosen - The oncologist, 2005 - academic.oup.com
… After over 30 years of theorizing, the use of angiogenesis inhibitors as anticancer therapy
has … makes them attractive therapeutic targets. A multitude of VEGF-targeted inhibitory agents …

[HTML][HTML] Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy

XJ Tang, XY Sun, KM Huang, L Zhang, ZS Yang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… This is an essential prerequisite for exosomes to be applied for targeted cancer therapy
because target orientation-related molecules from parent cells are also present in exosomes [8]. …

Improving the therapeutic potential of human granzyme B for targeted cancer therapy

G Hehmann-Titt, S Schiffer, N Berges, G Melmer… - Antibodies, 2013 - mdpi.com
Targeted therapeutic approaches are therefore preferred, … of highly-effective targeted therapies
with minimal side effects. … already demonstrated its potential for targeted cancer therapy. …

Extracellular matrix and its therapeutic potential for cancer treatment

J Huang, L Zhang, D Wan, L Zhou, S Zheng… - … and Targeted Therapy, 2021 - nature.com
… Therefore, a comprehensive understanding of ECM dysregulation in the TME would
contribute to the discovery of promising therapeutic targets for cancer treatment. Herein, we …

An overview of targeted cancer therapy

VV Padma - BioMedicine, 2015 - Springer
targets that determine therapeutic outcome. The molecularly targeted cancer therapies
have resulted in improving the lives of a large number of cancer patients. The successful …

The development of immunoconjugates for targeted cancer therapy

BG Smaglo, D Aldeghaither, LM Weiner - Nature Reviews Clinical …, 2014 - nature.com
… of the drug until it reaches its target. Conversely, many unconjugated antibodies are highly
specific for a cancer target, but have low therapeutic potential and can be repurposed as …

Novel approaches for targeted cancer therapy

V Guillemard, HU Saragovi - Current cancer drug targets, 2004 - ingentaconnect.com
… of selectivity in targeting tumor cells. Moreover, … drugs into targeted cells. As of January
1996, there were approximately 80 agents (excluding mAbs) approved for the treatment of cancer

Targeted cancer therapy: the next generation of cancer treatment

TA Baudino - Current drug discovery technologies, 2015 - ingentaconnect.com
… of targeted cancer treatment therapies. Although various targeted cancer treatment drugs
usually specific types of cancers for which each of the drugs will be therapeutically efficacious. …

Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential

Y Lu, E Sega, CP Leamon, PS Low - Advanced drug delivery reviews, 2004 - Elsevier
… ligand for targeted cancer therapies because it binds to a tumor-… to therapeutic agents,
folate-targeted cancer therapies can deliver therapeutic drugs specifically to FR-positive tumor

Molecularly targeted cancer therapy: some lessons from the past decade

M Huang, A Shen, J Ding, M Geng - Trends in pharmacological sciences, 2014 - cell.com
… in anticancer drug development. Nevertheless, molecularly targeted cancer therapy remains
… and remaining challenges in molecularly targeted cancer therapy, and proposes feasible …