VEGF-targeted therapy: therapeutic potential and recent advances
LS Rosen - The oncologist, 2005 - academic.oup.com
… After over 30 years of theorizing, the use of angiogenesis inhibitors as anticancer therapy
has … makes them attractive therapeutic targets. A multitude of VEGF-targeted inhibitory agents …
has … makes them attractive therapeutic targets. A multitude of VEGF-targeted inhibitory agents …
[HTML][HTML] Therapeutic potential of CAR-T cell-derived exosomes: a cell-free modality for targeted cancer therapy
XJ Tang, XY Sun, KM Huang, L Zhang, ZS Yang… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… This is an essential prerequisite for exosomes to be applied for targeted cancer therapy
because target orientation-related molecules from parent cells are also present in exosomes [8]. …
because target orientation-related molecules from parent cells are also present in exosomes [8]. …
Improving the therapeutic potential of human granzyme B for targeted cancer therapy
G Hehmann-Titt, S Schiffer, N Berges, G Melmer… - Antibodies, 2013 - mdpi.com
… Targeted therapeutic approaches are therefore preferred, … of highly-effective targeted therapies
with minimal side effects. … already demonstrated its potential for targeted cancer therapy. …
with minimal side effects. … already demonstrated its potential for targeted cancer therapy. …
Extracellular matrix and its therapeutic potential for cancer treatment
J Huang, L Zhang, D Wan, L Zhou, S Zheng… - … and Targeted Therapy, 2021 - nature.com
… Therefore, a comprehensive understanding of ECM dysregulation in the TME would
contribute to the discovery of promising therapeutic targets for cancer treatment. Herein, we …
contribute to the discovery of promising therapeutic targets for cancer treatment. Herein, we …
An overview of targeted cancer therapy
VV Padma - BioMedicine, 2015 - Springer
… targets that determine therapeutic outcome. The molecularly targeted cancer therapies
have resulted in improving the lives of a large number of cancer patients. The successful …
have resulted in improving the lives of a large number of cancer patients. The successful …
The development of immunoconjugates for targeted cancer therapy
BG Smaglo, D Aldeghaither, LM Weiner - Nature Reviews Clinical …, 2014 - nature.com
… of the drug until it reaches its target. Conversely, many unconjugated antibodies are highly
specific for a cancer target, but have low therapeutic potential and can be repurposed as …
specific for a cancer target, but have low therapeutic potential and can be repurposed as …
Novel approaches for targeted cancer therapy
V Guillemard, HU Saragovi - Current cancer drug targets, 2004 - ingentaconnect.com
… of selectivity in targeting tumor cells. Moreover, … drugs into targeted cells. As of January
1996, there were approximately 80 agents (excluding mAbs) approved for the treatment of cancer…
1996, there were approximately 80 agents (excluding mAbs) approved for the treatment of cancer…
Targeted cancer therapy: the next generation of cancer treatment
TA Baudino - Current drug discovery technologies, 2015 - ingentaconnect.com
… of targeted cancer treatment therapies. Although various targeted cancer treatment drugs …
usually specific types of cancers for which each of the drugs will be therapeutically efficacious. …
usually specific types of cancers for which each of the drugs will be therapeutically efficacious. …
Folate receptor-targeted immunotherapy of cancer: mechanism and therapeutic potential
… ligand for targeted cancer therapies because it binds to a tumor-… to therapeutic agents,
folate-targeted cancer therapies can deliver therapeutic drugs specifically to FR-positive tumor …
folate-targeted cancer therapies can deliver therapeutic drugs specifically to FR-positive tumor …
Molecularly targeted cancer therapy: some lessons from the past decade
… in anticancer drug development. Nevertheless, molecularly targeted cancer therapy remains
… and remaining challenges in molecularly targeted cancer therapy, and proposes feasible …
… and remaining challenges in molecularly targeted cancer therapy, and proposes feasible …
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