Advance of molecular imaging technology and targeted imaging agent in imaging and therapy

ZY Chen, YX Wang, Y Lin, JS Zhang… - BioMed research …, 2014 - Wiley Online Library
… into nanoparticles to construct multifunctional imaging agents which allow for … imaging, the
novel imaging agent including targeted imaging agent and multifunctional imaging agent, as …

Tumor detection using folate receptor-targeted imaging agents

EI Sega, PS Low - Cancer and Metastasis reviews, 2008 - Springer
… to FR-targeted therapies, FR-targeted imaging agents have … to respond to folate-targeted
therapies. This review focuses … acid to target PET agents, γ-emitters, MRI contrast agents and …

Detection of early prostate cancer using a hepsin-targeted imaging agent

KA Kelly, SR Setlur, R Ross, R Anbazhagan… - Cancer research, 2008 - AACR
… The goal of this project was to develop targeted imaging agents against an emerging, potential
new prostate cancer biomarker to improve prostate cancer detection. We choose HPN as …

Principles in the design of ligand-targeted cancer therapeutics and imaging agents

M Srinivasarao, CV Galliford, PS Low - Nature reviews Drug discovery, 2015 - nature.com
… into a target cell; and a therapeutic 'warhead'. Conversely, ligand-targeted imaging agents
… cleavable bridge, and the payload consists of an imaging, rather than a therapeutic, agent. …

… , synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging

H Xu, K Baidoo, AJ Gunn, CA Boswell… - Journal of medicinal …, 2007 - ACS Publications
… the imaging agents on the same vector, differences in the distribution of the agents would be
… This is one of the advantages of multimodality imaging agents such as the trifunctional agent

[图书][B] Handbook of targeted delivery of imaging agents

VP Torchilin - 1995 - books.google.com
… Scintigraphy remains the mother of all targeted imaging agents, as is well reflected in the
medical literature and the contents of this book. To be competitive, CT and MRI must overcome …

Targeted molecular imaging agents for cellular-scale bimodal imaging

HC Manning, T Goebel, RC Thompson… - Bioconjugate …, 2004 - ACS Publications
… Here we describe the first PBR-targeted MI agent that could facilitate MR imaging and, …
scale bimodal (MR and fluorescence) imaging. The MI agent described is a PK11195 (nanomolar …

Folate-targeted therapeutic and imaging agents for cancer

PS Low, SA Kularatne - Current opinion in chemical biology, 2009 - Elsevier
… While antibody-targeted drugs have been the first to enter … deliver attached imaging and
therapeutic agents selectively to … , folate-targeted drugs can be released inside their target cells …

Assessment of an 18F-labeled phosphoramidate peptidomimetic as a new prostate-specific membrane antigen–targeted imaging agent for prostate cancer

SE Lapi, H Wahnishe, D Pham, LY Wu… - Journal of Nuclear …, 2009 - Soc Nuclear Med
… the dipeptide motif for PSMA targeting, we have developed a … for PSMA-targeted delivery
for prostate cancer imaging and … as a targeting element for prostate cancer imaging. The …

Targeted imaging using ultrasound

PA Dayton, KW Ferrara - … of Magnetic Resonance Imaging: An …, 2002 - Wiley Online Library
Targeted ultrasound techniques combine ultrasound imaging technology with specific
contrast agents … Goals of targeted imaging include noninvasive detection of pathology using …