Biomaterial-assisted targeted modulation of immune cells in cancer treatment

H Wang, DJ Mooney - Nature materials, 2018 - nature.com
… and manipulate immune cells in vivo. In … targeted modulation of dendritic cells, T cells,
tumour-associated macrophages, myeloid-derived suppressor cells, B cells and natural killer cells

[HTML][HTML] Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
… strategies for in vivo targeted modulation of the immune system. We focus on approaches
targeting immune cells and lymphoid organs, excluding direct targeting of pathogens such as …

Advances in targeting cell surface signalling molecules for immune modulation

S Yao, Y Zhu, L Chen - Nature reviews Drug discovery, 2013 - nature.com
… that target cell surface signalling molecules on immune cells to drive immune responses
towards the desired direction. Advances in our understanding of the human immune system, …

MSCs: delivery routes and engraftment, celltargeting strategies, and immune modulation

TJ Kean, P Lin, AI Caplan, JE Dennis - Stem cells international, 2013 - Wiley Online Library
… T-cells and resulting in the loss of MSC inhibition of T-cell proliferation [43]. Indeed, several
more recent studies indicate that cell-to-cell contact between MSCs and immune cells may …

[HTML][HTML] Mechanisms of immune modulation in the tumor microenvironment and implications for targeted therapy

P Czajka-Francuz, MJ Prendes, A Mankan… - Frontiers in …, 2023 - frontiersin.org
… The presence of pre-existing immunity, defined as the infiltration of immune cells into the
tumor, seems to be crucial for the response to immunotherapies (3). Based on the …

Cell/bacteria‐based bioactive materials for cancer immune modulation and precision therapy

H Pan, M Zheng, A Ma, L Liu, L Cai - Advanced Materials, 2021 - Wiley Online Library
… Naturally derived bioactive materials, such as cell and … , can precisely target tumors and
effectively modulate immune … and targeting can be implemented by virtue of the immune cell

[HTML][HTML] Targeting inflammation with nanosized drug delivery platforms in cardiovascular diseases: immune cell modulation in atherosclerosis

A Cervadoro, R Palomba, G Vergaro… - … in Bioengineering and …, 2018 - frontiersin.org
targets at the plaque level, preventing systemic side effects (Jokerst and Gambhir, 2011;
Di Mascolo et al., 2013). Drug-loaded NPs targeting macrophages and other immune cells

Therapeutic targeting of trained immunity

WJM Mulder, J Ochando, LAB Joosten… - Nature reviews Drug …, 2019 - nature.com
… to target innate immune cells and regulate trained immunity to achieve long-term therapeutic
benefits in a range of immune… initial experience modulating trained immunity therapeutically …

Glycan-based cell targeting to modulate immune responses

T Johannssen, B Lepenies - Trends in Biotechnology, 2017 - cell.com
… antigen-presenting cells are attractive targets to shape immune … has successfully enabled
CLR targeting. In this review, we … highlight CLR targeting approaches for immune modulation. …

Polymeric micro-and nanoparticles for immune modulation

E Ben-Akiva, SE Witte, RA Meyer, KR Rhodes… - Biomaterials …, 2019 - pubs.rsc.org
… agents targeted to a variety of immune cell types including APCs, T … immune cell type
that it modulates, this review is structured based on these cell types: antigen presenting cells