Nanoplatforms for targeted molecular imaging in living subjects

W Cai, X Chen - Small, 2007 - Wiley Online Library
… passive targeting mechanisms based on enhanced permeability and retention (EPR)
effects.19, 20 This Review will focus on targeted molecular imaging, and the passive targeting of …

Peptide-based probes for targeted molecular imaging

S Lee, J Xie, X Chen - Biochemistry, 2010 - ACS Publications
Targeted molecular imaging techniques have become … low targeting efficiency; thus, the
use of molecularly targeted imaging probes is needed depending on different imaging modalities…

Targeted molecular imaging in oncology

DJ Yang, EE Kim, T Inoue - Annals of nuclear medicine, 2006 - Springer
… PET and SPECT use radiotracers to image, map and measure target site activities (… molecular
imaging modalities. 1-3 Reliable molecular imaging assays that assess (l) cellular targets

Advance of molecular imaging technology and targeted imaging agent in imaging and therapy

ZY Chen, YX Wang, Y Lin, JS Zhang… - BioMed research …, 2014 - Wiley Online Library
… into nanoparticles to construct multifunctional imaging agents which allow for … molecular
imaging, the novel imaging agent including targeted imaging agent and multifunctional imaging

Nanotechnology for molecular imaging and targeted therapy

SA Wickline, GM Lanza - Circulation, 2003 - Am Heart Assoc
… Elements fundamental to the growth of molecular imaging are exemplified in summary
statements from the second Biomedical Imaging Symposium: Visualizing the Future of Biology …

Molecular imaging: current status and emerging strategies

MA Pysz, SS Gambhir, JK Willmann - Clinical radiology, 2010 - Elsevier
targeted US imaging.32, 33 In summary, current clinical molecular imaging is mostly …
with PET and SPECT, and several targeted radiopharmaceuticals for both imaging and dual-…

A novel clinically translatable fluorescent nanoparticle for targeted molecular imaging of tumors in living subjects

J Gao, K Chen, R Luong, DM Bouley, H Mao, T Qiao… - Nano …, 2012 - ACS Publications
The use of quantum dots (QDs) in biomedical research has grown tremendously, yet successful
examples of clinical applications are absent due to many clinical concerns. Here, we …

Enzymatic single-chain antibody tagging: a universal approach to targeted molecular imaging and cell homing in cardiovascular disease

HT Ta, S Prabhu, E Leitner, F Jia… - Circulation …, 2011 - Am Heart Assoc
… We demonstrate this novel use of sortase A for the selective labeling of imaging contrast
particles and live cells with scFvs suitable for targeted molecular imaging and cell homing. This …

Targeted molecular imaging agents for cellular-scale bimodal imaging

HC Manning, T Goebel, RC Thompson… - Bioconjugate …, 2004 - ACS Publications
target for molecular imaging. In this paper, the authors report cellular uptake and multimodal
(MRI and fluorescence) imaging … PBR targeted lanthanide chelate molecular imaging agent. …

Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy

C Tassa, SY Shaw, R Weissleder - Accounts of chemical research, 2011 - ACS Publications
… of conjugation methods has enabled CLIO’s use for molecular imaging, sensitive and rapid
ex vivo detection of analytes, and the targeted delivery of therapy. Ongoing and future efforts …