… are capable of targeted protein knockdown in various tissues … immune-captured proteins or
enrich RIPK2 levels, increasing … suitable therapeutic agents and tools, the linker composition …

… Targeted protein degradation (TPD), a highly promising therapeutic strategy in drug discovery,
is gaining increasing … research expands the scope of the E3 ligase ligand toolbox and …

… Targeted protein degradation (TPD) is an emerging … availability of a diverse chemical toolkit
of E3 recruiters will … Excitingly, this study expands the repertoire of strategies available for the …

… help greatly in expanding the TPD toolbox by providing a choice of targets paired with their
… cohort of proteins with a single E3 ligase. The motifs can be potentially targeted with peptides …

… the first targeted protein degradation method reported in T. brucei, expanding the current
molecular toolkits … Rapid protein degradation makes it very useful for protein functional studies. …

… Hijacking the ubiquitin proteasome system to elicit targeted protein degradation (TPD) has …
–Tn3 fusion proteins efficiently degraded their respective target proteins through the ubiquitin …

… These controllable TPD systems expand the synthetic biology toolbox, offering powerful
tools for biological studies and holding promise for advancing gene and cell-based precision …

… of a cell biologist's toolkit, in both cases protein depletion is … with genetic engineering expands
the possibilities for … the generation of AID-tagged target proteins in human cell lines and …

… tools innovated to target gene expression at RNA level and protein level, expanding to
innovations of targeted tools for … on various tools for protein degradation that has been evolved. …

… degradation, and multiplexed phosphoproteomics to investigate signaling by individual
PPPs on a global level, which is currently limited by the lack of tools for specific interrogation. …