… allows simultaneous scanning of an entire group of fragment ions from a targeted metabolite
at high resolution, and has proven to be a powerful means of targeted quantification. …

… Most late model high-resolution mass spectrometers (HRMS) … ) or, if needed, in a more
targeted SIM or MS 2 mode. Usual LC-… The use of one MS platform from targeted quantification to …

… of the overall paradigm of targeted experiments, by the … a full MS/MS fragmentation pattern,
and the quantification based on … screening or precise targeted quantification using calibrated …

… has been the major method used for targeted quantification of a protein, providing good
sensitivity … platform for targeted protein quantification is highlighted by its excellent resolution and …

… a nonbiased mass spectrometry-… quantify multiple different forms of the target proteins and
their interacting partners. The ability to detect and quantify multiple different forms of the target …

… all generated MS/MS fragment ions are monitored in parallel on a high-resolution, accurate
… PRM has been used for targeted peptide quantification in high-resolution LC-MS platforms, …

… Non-targeted and suspect analyses with liquid chromatography/electrospray/high-resolution
mass spectrometry (LC/… Here, we present an approach to address the challenge to quantify …

For quantitative analysis of small-molecule drugs, LC–MS is considered the gold standard.
However, focusing on peptide drugs, the majority of peptide development programs still rely …

… quantify a set of proteins reproducibly, completely, and with high sensitivity. Given the immense
benefit that high resolution … targeted proteomics domain as well. Here, we propose a new …

… We then examined the optimized MS/MS spectra to select 1–6 fragments of relatively
high abundance and large m/z for target quantification. Skyline software was used here to …