… cell behaviours which appear shared across disease states. It has been suggested … health
and disease and discusses whether neutrophil functions could be targeted to improve health …

… diseases (mitochondriopathies) and many other infectious and non-infectious diseases …
, diabetes, obesity and cardiovascular diseases. Mitochondria therefore become an attractive …

… Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and cancers, …

… which influence disease … treatment to impact on mortality and reverse the disease process
is because of the heterogeneous nature of the condition. Identification and targeted treatment …

… In this Review, we discuss several examples of this therapeutic strategy that seem to be
successful, and consider their implications for the future of immune-targeted treatments. We …

… Until recently, patients who have the same type and stage of cancer all receive the same
treatment. It has been established, however, that individuals with the same disease respond …

… people die as a result of the disease. 5-year survival rates vary … treatment for patients with
lung cancer and the promise of precision medicine, with special emphasis on new targeted …

… associated with specific diseases are discovered and targeted therapies are developed. …
disease management. In some areas of medicine, patient-tailored risk prediction and treatment …

… these targeted therapies. We review recent progress in the development of targeted treatments
for … Most patients with lung cancer present with metastatic disease at diagnosis. For many …

… stage cancer, the recurrent and metastatic disease remains a major cause of cancer death.
… therapies to treat cervical cancer. In recent decades, research on treatment strategies has …