Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries

X Han, J Zhang, J Liu, H Wang, F Du, X Zeng, C Guo - Apoptosis, 2023 - Springer
… This article summarizes the metabolic regulatory mechanisms of ferroptosis and the
relationship between ferroptosis and myocardial infarction as well as myocardial ischemia/…

[HTML][HTML] Ferroptosis as a novel therapeutic target for cardiovascular disease

X Wu, Y Li, S Zhang, X Zhou - Theranostics, 2021 - ncbi.nlm.nih.gov
… years, ferroptosis has been found to play critical roles in cardiomyopathy, myocardial infarction,
… This article reviews the mechanisms by which ferroptosis is initiated and controlled and …

[HTML][HTML] Targeting ferroptosis against ischemia/reperfusion cardiac injury

J Lillo-Moya, C Rojas-Solé, D Muñoz-Salamanca… - Antioxidants, 2021 - mdpi.com
ferroptosis is one of the major drivers of myocardial infarction [9]. … ferroptosis is a major
driver of injury occurring in myocardial infarction and can be a promising target to reduce infarct

Targeting ferroptosis by polydopamine nanoparticles protects heart against ischemia/reperfusion injury

Y Zhang, X Ren, Y Wang, D Chen, L Jiang… - … applied materials & …, 2021 - ACS Publications
… cardiac function and reduced myocardial infarct size. We also … a ferroptosis inhibitor for
alleviating myocardial I/R injury. This study may provide new perspectives to address myocardial I/…

[HTML][HTML] The role of ferroptosis in adverse left ventricular remodeling following acute myocardial infarction

K Komai, NK Kawasaki, JK Higa, T Matsui - Cells, 2022 - mdpi.com
… clinical application of therapies that target and suppress ferroptosis at the initial infarct site,
as well as inflammation caused by the infarcted tissue and cells recruited to the infarct site. …

Targeting ferroptosis: pathological mechanism and treatment of ischemia‐reperfusion injury

X Li, N Ma, J Xu, Y Zhang, P Yang, X Su… - Oxidative Medicine …, 2021 - Wiley Online Library
… that C3G effectively alleviated myocardial I/R injury by inhibiting ferroptosis both in vivo
and in vitro [72]. C3G treatment could reduce myocardial infarction area, inhibit pathological …

[HTML][HTML] Targeting ferroptosis to treat cardiovascular diseases: a new continent to be explored

F Huang, R Yang, Z Xiao, Y Xie, X Lin, P Zhu… - Frontiers in Cell and …, 2021 - frontiersin.org
myocardial injury by blocking ferroptosis pathway. In this review, we systematically described
the mechanisms of ferroptosis and discussed the role of ferroptosisMyocardial Infarction (…

Ferroptosis inhibitors as potential new therapeutic targets for cardiovascular disease

Z Shaghaghi, S Motieian, M Alvandi… - Mini Reviews in …, 2022 - ingentaconnect.com
… In this study, it was found that phenothiazine prevents and causes myocardial infarction,
can be a valuable tool, and has good pharmacokinetic properties for administration [82]. …

[HTML][HTML] Targeting iron metabolism and ferroptosis as novel therapeutic approaches in cardiovascular diseases

Y Chen, X Li, S Wang, R Miao, J Zhong - Nutrients, 2023 - mdpi.com
… Intriguingly, DFO has been exhibited to alleviate ferroptosis and reduce myocardial infarct
size in myocardial I/R injury by potentiating expression of GPX4 and preventing excessive …

Ferroptosis in myocardial infarction: not a marker but a maker

X Wang, S Kang - Open Biology, 2021 - royalsocietypublishing.org
targets for myocardial infarction (MI) will play an important role in early diagnosis and improving
prognosis. Ferroptosis, a … did not prevent the occurrence of ferroptosis, but iron chelating …