Targeting ferroptosis: pathological mechanism and treatment of ischemia‐reperfusion injury

X Li, N Ma, J Xu, Y Zhang, P Yang, X Su… - Oxidative Medicine …, 2021 - Wiley Online Library
… of I/R injury. Herein, we analytically review the pathological mechanism and targeted treatment
of ferroptosis in I/R … of myocardial I/R injury, cerebral I/R injury, and ischemic renal injury. …

Targeting ferroptosis as a promising therapeutic strategy for ischemia-reperfusion injury

Y Pan, X Wang, X Liu, L Shen, Q Chen, Q Shu - Antioxidants, 2022 - mdpi.com
… mechanism and targeted therapeutic strategies of ferroptosis in I/R … on ferroptosis in I/R injury,
including ferroptosis regulatory … the therapeutic application of ferroptosis regulators, hoping …

Targeting ferroptosis against ischemia/reperfusion cardiac injury

J Lillo-Moya, C Rojas-Solé, D Muñoz-Salamanca… - Antioxidants, 2021 - mdpi.com
ferroptosis is a major driver of injury occurring in myocardial infarction and can be a promising
target … However, we have to be aware of the advantage and disadvantage of ferroptosis

Ferroptosis: a novel therapeutic target for ischemia-reperfusion injury

Y Chen, H Fan, S Wang, G Tang, C Zhai… - Frontiers in Cell and …, 2021 - frontiersin.org
… as a new therapeutic target for the management of I/R injury. This review … of ferroptosis and
discusses its relationship with I/R injury, as well as potential treatment strategies targeting it. …

Targeting ferroptosis: a novel insight against myocardial infarction and ischemia–reperfusion injuries

X Han, J Zhang, J Liu, H Wang, F Du, X Zeng, C Guo - Apoptosis, 2023 - Springer
… the metabolic regulatory mechanisms of ferroptosis and the relationship between ferroptosis
and myocardial infarction as well as myocardial ischemia/reperfusion injuries, which might …

Ferroptosis—a new dawn in the treatment of organ ischemia–reperfusion injury

L Zhou, S Han, J Guo, T Qiu, J Zhou, L Shen - Cells, 2022 - mdpi.com
… the pathological mechanisms and therapeutic targets of ferroptosis in IRI. … in ferroptosis
pathogenesis, ferroptosis evidence in organ IRIs, and associated potential therapeutic targets

Targeting ferroptosis by polydopamine nanoparticles protects heart against ischemia/reperfusion injury

Y Zhang, X Ren, Y Wang, D Chen, L Jiang… - … applied materials & …, 2021 - ACS Publications
… of using PDA NPs as a ferroptosis inhibitor for alleviating myocardial I/R injury. This study
may provide new perspectives to address myocardial I/R injury and suggest PDA NPs as a …

Targeting ferroptosis in ischemia/reperfusion renal injury

K Thapa, TG Singh, A Kaur - Naunyn-Schmiedeberg's Archives of …, 2022 - Springer
… cell damage. Thus, this review emphasized the role of ferroptosis and its inhibition in renal
IRI. Also, Pharmacological modulation of ferroptosis mechanism in renal I/R injury has been …

[HTML][HTML] MiR-20a-5p alleviates kidney ischemia/reperfusion injury by targeting ACSL4-dependent ferroptosis

L Shi, Z Song, Y Li, J Huang, F Zhao, Y Luo… - American Journal of …, 2023 - Elsevier
… an endogenous inhibitor of ACSL4 and regulating kidney ferroptosis. Our results suggest
that miR-20a-5p might be a new therapeutic target for alleviating the damage induced by IRI. …

Ferroptosis: opportunities and challenges in myocardial ischemia‐reperfusion injury

W Zhao, Y Zhou, T Xu, Q Wu - Oxidative Medicine and Cellular …, 2021 - Wiley Online Library
damage-associated molecular patterns (DAMPs) after heart transplantation [87]. Therefore,
targeted ferroptosis … heart transplantation after coronary artery reperfusion. Other drugs, such …