过去一年中添加的文章,按日期排序

Role of natural products in cardiovascular disease

Q Dong, G Dai, N Quan, Q Tong - Molecular and Cellular Biochemistry, 2024 - Springer
4 天前 - target genes involved in inflammation (interleukins and COX2) [31], Lycopene can
suppress inflammatory … is needed to develop improved targeted therapies with the aim to …

Role of Recombinant Proteins for Treating Rheumatoid Arthritis

MS SasaniSasani, Y Moradi - Avicenna Journal of …, 2024 - publish.kne-publishing.com
4 天前 - … of recombinant proteins that target specific signaling pathways involved in the
development of RA to alleviate symptoms and slow the progression of the disease. This article …

Post-translational oxidative modification of fibrinogen and its role in thrombotic risk in endometriosis

E Fini - 2024 - flore.unifi.it
4 天前 - … Among plasma proteins, fibrinogen represents the major target for post-translational …
in chronic inflammatory diseases, cardiovascular diseases and immune disease. Indeed, it …

Oxidative Stress as a Target for Non-Pharmacological Intervention in MAFLD: Could There Be a Role for EVOO?

A Seidita, A Cusimano, A Giuliano, M Meli, A Carroccio… - Antioxidants, 2024 - mdpi.com
4 天前 - … -inflammatory cytokines. This close pathogenetic link has been a key stimulus in the
search for therapeutic approaches targeting … in MAFLD treatment that target oxidative stress …

Gut microbiota-derived acetate attenuates lung injury induced by influenza infection via protecting airway tight junctions

L Hu, L Sun, C Yang, DW Zhang, YY Wei… - Journal of Translational …, 2024 - Springer
4 天前 - … be a potential therapeutic target for patients with IAV infection. … disease [6], and
allergic airway disease [7]. Considering the vital importance of the gut-lung axis in lung diseases

Spesolimab: A Novel Interleukin-36 Receptor Monoclonal Antibody for the Treatment of Generalized Pustular Psoriasis

RP Sable, AG Gawai, VJ Rajput, SA Urkunde… - Asian Journal of …, 2024 - ajprd.com
4 天前 - … to favor the pro-inflammatory activity, which is critical in the … of targeted biological
therapies for the disease. This article … on evidence-based targeted biologic therapy and clinical …

Exploring the Activation Mechanism of the GPR183 Receptor

L Hu, K An, Y Zhang, C Bai - The Journal of Physical Chemistry B, 2024 - ACS Publications
4 天前 - … , understanding the activation process of GPR183 through molecular dynamic
simulations offers valuable kinetic insights that can aid in the development of targeted therapies. …

[HTML][HTML] Tissue gene expression profiles and communication networks inform candidate blood biomarker identification in psoriasis and atopic dermatitis

J Soul, E Carlsson, SR Hofmann, S Russ, J Hawkes… - Clinical …, 2024 - Elsevier
5 天前 - Targeted validation of selected … inflammatory diseases. Psoriasis and AD are
characterized by transcriptional dysregulation in T cells and keratinocytes that may be targeted

Lipoprotein (a)-Related Inflammatory Imbalance: A Novel Horizon for the Development of Atherosclerosis

T Qin, TY Ma, K Huang, SJ Lu, JH Zhong… - Current Atherosclerosis …, 2024 - Springer
5 天前 - … This link enhances our comprehension of cardiovascular disease mechanisms and
suggests that targeting IL-6 could be valuable in preventing and treating CVD [75]. Müller et …

[HTML][HTML] Cartilage Decellularized Matrix Hydrogel Loaded with Protocatechualdehyde for Targeted Epiphycan Treatment of Osteoarthritis

J Huang, Z Bu, W Liu, Z Zhou, J Hu, J Yu, H Wang… - Materials Today Bio, 2024 - Elsevier
5 天前 - … Having previously established the regulatory effects of EPYC on OA and IL-17A,
we now proceed to investigate novel therapeutic strategies that target EPYC. PAH, an active …