3 天前 - … Epigenetic silencing of miRNA-143 regulates apoptosis by targeting BCL2 in
human … -143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal …

4 天前 - Chronic wounds impact 2.5% of the United States population and will continue to
be a major clinical challenge due to increases in population age, chronic disease diagnoses, …

4 天前 - … , a critical mediator of inflammation implicated in disease progression. High glucose
levels, a … as a therapeutic target to mitigate inflammation and improve disease outcomes. …

4 天前 - … Emerging therapies focus on targeting specific molecules that may be involved in
the inflammatory pathway of this disease. These medications include naltrexone, apremilast, …

4 天前 - … serve as a potential therapeutic target for sepsis-induced AKI. Although studies
have been conducted on the mechanisms of action of SIRTs in anti-inflammation, anti-autophagy…

4 天前 - … , and therapeutic target for IBD. This review also explores emerging therapeutic
advancements that target gut … , nutritional therapies, microbiome/probiotic engineering, phage …

4 天前 - … therapeutic targeting strategies and their limitations, discussing both knowledge
gaps and promising future directions to enhancing clinical efficacy in allergic disease …

4 天前 - … diverse therapeutic actions against various chronic diseases, emphasizing its targeted
… , that support its therapeutic efficacy across different disease conditions. Furthermore, in…

4 天前 - … is rising, releasing a pro-inflammatory SASP responsible for … potential therapeutic
interventions for AD targeting tau protein … and targeted senescent cell-based therapies holds …

4 天前 - … investigated for their therapeutic potential in treating different diseases. Interestingly
25% … The majority of these drugs were unveiled through targeted studies specifically aimed …