过去一年中添加的文章，按日期排序
Unravelling the ties that bind: The intersection of obesity, osteoarthritis, and inflammatory pathways with emphasis on glucagon‐like peptide‐1 agonists
N Jamal, W Hollabaugh, L Scott… - Clinical Obesity, 2024 - Wiley Online Library
6 天前 - … underlying of mechanisms of inflammation and potential therapeutic interventions
targeting both diseases. Through examination of the shared inflammatory pathway of obesity …
targeting both diseases. Through examination of the shared inflammatory pathway of obesity …
Klotho: molecular mechanisms and emerging therapeutics in central nervous system diseases
6 天前 - … klotho can be a key therapeutic target in CNS diseases such as amyotrophic lateral
sclerosis, Parkinson’s disease, stroke, and Alzheimer’s disease. Reviewing the literature …
sclerosis, Parkinson’s disease, stroke, and Alzheimer’s disease. Reviewing the literature …
Data Mining and in Silico Analysis of Ethiopian Traditional Medicine: Unveiling the Therapeutic Potential of Rumex abyssinicus Jacq.
LE Bultum, G Kim, SW Lee, D Lee - Cell Biochemistry and Biophysics, 2024 - Springer
6 天前 - … their related human target genes/proteins. Utilizing this extensive compound-target
data, we identified 756 human target genes/proteins associated with these phytochemicals. …
data, we identified 756 human target genes/proteins associated with these phytochemicals. …
[引用][C] … The interleukin‐2 receptor pathway agonist rezpegaldesleukin (REZPEG) for the rescue of regulatory T cells in chronic inflammatory and autoimmune diseases
C Fanton, J Zalevsky - Wiley Online Library
6 天前 - … and chronic inflammatory disease management, increased patient compliance,
convenience, and tolerability while also minimizing the risk of off- target Tcon stimulation. In two …
convenience, and tolerability while also minimizing the risk of off- target Tcon stimulation. In two …
[HTML][HTML] Obesity-induced fibrosis in osteoarthritis: pathogenesis, consequences and novel therapeutic opportunities
J Henriques, F Berenbaum, A Mobasheri - Osteoarthritis and Cartilage …, 2024 - Elsevier
6 天前 - … Non-steroidal anti-inflammatory drugs are prescribed to decrease pain and
inflammation, but they do not target the pathogenic mechanisms in OA. Furthermore, they can have …
inflammation, but they do not target the pathogenic mechanisms in OA. Furthermore, they can have …
[HTML][HTML] Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular …
6 天前 - … anti-inflammatory responses, and modulating pain, making sEH a key target for
therapeutic … their potential as natural therapeutic agents for managing cardiovascular and …
therapeutic … their potential as natural therapeutic agents for managing cardiovascular and …
BLOOD PRESSURE TRAJECTORIES AND MORTALITY AMONG PEOPLE WITH AND WITHOUT HIV IN A UNITED STATES-BASED COHORT STUDY
L Sadinski - 2024 - cdr.lib.unc.edu
6 天前 - … Having a systolic blood pressure between 110 and 130 mm Hg (ie, within the systolic
target … The hazard of all-cause mortality declined with increasing time in the systolic target …
target … The hazard of all-cause mortality declined with increasing time in the systolic target …
[HTML][HTML] Novel Small Molecules with Anti-Inflammatory and Anti-Angiogenic Activity in a Mouse Model of Oxygen-Induced Retinopathy
AS Dayoub, E Acharya, A Dibas, HP Jones, S Acharya - Cells, 2024 - mdpi.com
6 天前 - … The results are consistent with our hypothesis that targeting the dual TLR2/4
pathway will reduce inflammation, angiogenesis, and vaso-obliteration in vitro and in vivo and …
pathway will reduce inflammation, angiogenesis, and vaso-obliteration in vitro and in vivo and …
Autoinflammatory diseases associated with IL-18
6 天前 - … Measuring IL-18 levels in serum can aid in the diagnosis, prognosis, and monitoring
of these diseases. Therapies targeting IL-18 and its signaling pathways are currently under …
of these diseases. Therapies targeting IL-18 and its signaling pathways are currently under …
Cardiovascular Disease and Thrombosis: Intersections with the Immune System, Inflammation, and the Coagulation System
6 天前 - … , we can discover novel therapeutic approaches that specifically target these
complex … disease processes. This review examines the interplay between inflammation and …
complex … disease processes. This review examines the interplay between inflammation and …