… The challenges in targeting inflammation in any chronic inflammatory disease lie in three
properties that are characteristic of processes that are critical for evolutionary survival: …

… of the immunopathogenesis of inflammatory bowel disease (IBD) has opened new avenues
for developing targeted therapies. These advances in treatment options targeting different …

… inflammatory diseases, summarize the leading drugs used to regulate macrophages, and
review drug delivery systems designed to target … macrophage-targeted drug delivery systems. …

… of biological activities in both innate and adaptive immune responses, and GM-CSF seems
likely to become an important novel therapeutic target in several inflammatory diseases. …

… therapeutic possibilities, largely for infectious diseases and sepsis, but also for inflammatory
diseases … This review focuses on signal transduction, highlighting drugs that currently target …

… Recently, new classes of compounds that target IL-1 production or processing, or regulatory
… of inflammatory disease. Such compounds will have wide utility in numerous inflammatory …

… Targeting IL-6 has been a promising new approach for the treatment … inflammatory and
autoimmune diseases. This could shake up the biologics market in chronic inflammatory diseases…

… in potent therapeutic effects in a wide variety of rodent models of inflammatory diseases, …
Although these findings highlight the potential of NLRP3 as a drug target, an understanding …

… in the inflammatory lungs of acute pneumonia mice for anti-inflammatory therapy. …
technology provides a universal platform for targeted inflammation neutralization treatment. …

… is a hallmark of the disease. The ultimate benefit of such targeted therapy will depend on
the delicate balance between suppressing inflammation and interfering with normal cellular …