Nanocarriers in therapy of infectious and inflammatory diseases

U Ikoba, H Peng, H Li, C Miller, C Yu, Q Wang - Nanoscale, 2015 - pubs.rsc.org
inflammatory diseases such as bone inflammation, skin inflammation, and internal inflammation
This section explores the uses of nanotechnology in order to target inflammatory areas in …

Targeting JAK/STAT signaling pathway in inflammatory diseases

CJ Malemud, E Pearlman - … Signal Transduction Therapy, 2009 - ingentaconnect.com
… in some inflammatory diseases of the visual system have emerged, this information has not
yet translated into developing JAK/STAT inhibitors for use in clinical therapy of eye diseases. …

[HTML][HTML] Targeting the notch signaling pathway in chronic inflammatory diseases

PF Christopoulos, TT Gjølberg, S Krüger… - Frontiers in …, 2021 - frontiersin.org
… sections, we discuss some chronic inflammatory diseases where Notch signaling seem
to play a role in pathogenesis, and thus, may represent a potential novel therapeutic target. …

JAK inhibition as a therapeutic strategy for immune and inflammatory diseases

DM Schwartz, Y Kanno, A Villarino, M Ward… - Nature reviews Drug …, 2017 - nature.com
… for novel therapeutic strategies for immune and inflammatory diseases. If targeting specific
… , an obvious alternative strategy is to target the action of different cytokines inside the cell. …

[HTML][HTML] Atherosclerosis is an inflammatory disease which lacks a common anti-inflammatory therapy: how human genetics can help to this issue. A narrative review

C Fava, M Montagnana - Frontiers in Pharmacology, 2018 - frontiersin.org
… point for the inflammatory hypothesis has been finally reached: atherosclerosis is an
inflammatory disease which can be targeted by a specific anti-inflammatory therapy. But the drug to …

Gene therapy targeting nuclear factor-κB: towards clinical application in inflammatory diseases and cancer

SW Tas, MJBM Vervoordeldonk… - Current gene therapy, 2009 - ingentaconnect.com
… The transcription factor nuclear factor-κB (NF-κB) is a key regulator of inflammation and
therefore plays a key role in a wide range of inflammatory diseases [1].The mammalian NF-κB/…

Jakpot! New small molecules in autoimmune and inflammatory diseases

K Ghoreschi, M Gadina - Experimental dermatology, 2014 - Wiley Online Library
… The critical role of cytokines in the pathogenesis of psoriasis: Targeted therapies inhibiting
extracellular cytokine actions and the new approach of blocking intra-cellular cytokine …

Targeting RAGE signaling in inflammatory disease

BI Hudson, ME Lippman - Annual review of medicine, 2018 - annualreviews.org
… pathobiology of RAGE in inflammatory disease, and the … Targeting RAGE, with complementary
combinational approaches, could yield novel therapies for chronic inflammatory disease

Targeting SHP2 as a therapeutic strategy for inflammatory diseases

Y Liu, X Yang, Y Wang, Y Yang, D Sun, H Li… - European Journal of …, 2021 - Elsevier
… , including cancer-related inflammation, neurodegenerative diseases and metabolic diseases.
In this paper, the roles of SHP2 in inflammatory diseases of various physiological systems …

[HTML][HTML] Tyk2 targeting in immune-mediated inflammatory diseases

L Rusiñol, L Puig - International Journal of Molecular Sciences, 2023 - mdpi.com
inflammatory cascades and have become a major focus of research, yielding novel therapies
for immune-mediated inflammatory diseases … as a promising therapeutic target, with …