Emerging role of extracellular vesicles in inflammatory diseases

EI Buzas, B György, G Nagy, A Falus… - Nature Reviews …, 2014 - nature.com
… and apoptotic vesicles, have therapeutic potential and might be used as biomarkers for
inflammatory diseases. Therefore, molecular diagnostics and targeted therapy could benefit from …

Targeting CD30/CD30L in oncology and autoimmune and inflammatory diseases

E Oflazoglu, IS Grewal, H Gerber - Therapeutic targets of the TNF …, 2009 - Springer
… as therapeutic targets in hematologic malignancies, autoimmune and inflammatory diseases
the pharmacodynamic effects of specific therapeutic compounds targeting the CD30/CD30L …

Nanomedicines for inflammatory diseases

FA Khaja, OMY Koo, H Önyüksel - Methods in enzymology, 2012 - Elsevier
… of inflammatory diseases would exceed 100; hence, this chapter will focus on conditions
where the availability of effective long-term therapy … for inflammation by the targeted delivery of …

Immune-mediated inflammatory disease therapeutics: past, present and future

IB McInnes, EM Gravallese - Nature Reviews Immunology, 2021 - nature.com
targeting of immune pathways in IMIDs, it was recognized that the best disease outcomes
occur when inflammation is … aggressive use of targeted therapies to control inflammation 5,20 . …

Bioresponsive drug delivery systems for the treatment of inflammatory diseases

Y Dou, C Li, L Li, J Guo, J Zhang - Journal of controlled release, 2020 - Elsevier
… systems for targeted treatment of inflammatory diseases. Herein … delivery systems for the
management of inflammatory diseases. … trigger for targeted therapy of inflammatory diseases. …

miRNAs as therapeutic targets in inflammatory disease

Q Lu, R Wu, M Zhao, A Garcia-Gomez… - Trends in pharmacological …, 2019 - cell.com
… treatments targeting abnormally expressed miRNAs for inflammatoryinflammatory diseases,
we provide a broad perspective on the common roles of certain miRNAs in these diseases, …

Interleukin-6: from an inflammatory marker to a target for inflammatory diseases

M Rincon - Trends in immunology, 2012 - cell.com
target in inflammatory disease. Here, I discuss how this cytokine has evolved from being a
marker of inflammation to a successful target to control inflammation… of inflammatory diseases. …

Targeting B cells in immune-mediated inflammatory disease: a comprehensive review of mechanisms of action and identification of biomarkers

T Dörner, N Kinnman, PP Tak - Pharmacology & therapeutics, 2010 - Elsevier
… , particularly using anti-CD20 treatment, has provided proof of concept that targeting B
cells … -mediated inflammatory disease. In this review, the mechanisms of action of B cell-targeting

Targeting chemokine receptors in chronic inflammatory diseases: an extensive review

PJ Koelink, SA Overbeek, S Braber, P de Kruijf… - Pharmacology & …, 2012 - Elsevier
… in inflammatory diseases of the airways (asthma and COPD), the intestinal tract (inflammatory
bowel diseases)… more effective therapeutic approaches for chronic inflammatory diseases. …

Targeting the S1P receptor signaling pathways as a promising approach for treatment of autoimmune and inflammatory diseases

B Stepanovska, A Huwiler - Pharmacological research, 2020 - Elsevier
… lead to diseases [21,22]. S1PRs have become an attractive pharmacological target to interfere
… to various auto-immune and inflammatory diseases; the discovery of fingolimod and its …