[HTML][HTML] Alterations of HDL's to piHDL's proteome in patients with chronic inflammatory diseases, and HDL-targeted therapies

V Vyletelová, M Nováková, Ľ Pašková - Pharmaceuticals, 2022 - mdpi.com
… or intestine, can lead to systemic inflammation, which may aggravate or … inflammatory
diseases is low-grade systemic inflammation, usually characterised by increased pro-inflammatory

Obesity alters pathology and treatment response in inflammatory disease

SP Bapat, C Whitty, CT Mowery, Y Liang, A Yoo… - Nature, 2022 - nature.com
disease with prominent T H 17 inflammation. We also observed divergent responses to biologic
therapies targeting … protected lean mice but exacerbated disease in obese mice. Single-…

[HTML][HTML] NLRP3 inflammasome and inflammatory diseases

Z Wang, S Zhang, Y Xiao, W Zhang, S Wu… - … medicine and cellular …, 2020 - hindawi.com
… plays a vital role in regulating inflammation. In this review, NLRP3 … in inflammatory diseases,
interactions with autophagy, and targeted therapeutic approaches in inflammatory diseases

A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases

N Arulkumaran, RJ Unwin, FWK Tam - Expert opinion on …, 2011 - Taylor & Francis
… is an important therapeutic target in inflammatory diseases. … in inflammatory diseases,
focusing on potential therapeutic applications of selective P2X7R antagonists as anti-inflammatory

Biologic targeting in the treatment of inflammatory bowel diseases

M Bosani, S Ardizzone, GB Porro - Biologics: Targets and Therapy, 2009 - Taylor & Francis
inflammation. Cytokines may therefore be a logical target for inflammatory bowel disease
therapy … Biotechnology agents targeted against TNF, leukocyte adhesion, Th1 polarization, T …

[HTML][HTML] Emerging role of METTL3 in inflammatory diseases: mechanisms and therapeutic applications

B Song, Y Zeng, Y Cao, J Zhang, C Xu, Y Pan… - Frontiers in …, 2023 - frontiersin.org
… In conclusion, we focus on the therapeutic application of METTL3 in inflammatory diseases.
inflammatory diseases will contribute to the development of improved targeted therapies and …

[HTML][HTML] Targeting C-reactive protein in inflammatory disease by preventing conformational changes

JR Thiele, J Zeller, H Bannasch, GB Stark… - … of inflammation, 2015 - hindawi.com
… the formation of proinflammatory mediators in ubiquitous inflammatory cascades has pushed
therapeutic strategies by targeting pCRP dissociation in inflammation. In this respect, the …

[HTML][HTML] Macrophage targeted theranostics as personalized nanomedicine strategies for inflammatory diseases

SK Patel, JM Janjic - Theranostics, 2015 - ncbi.nlm.nih.gov
Inflammatory disease management poses challenges due to the complexity of inflammation
… simultaneous imaging and treatment of inflammatory diseases. Theranostics could facilitate …

Tristetraprolin as a therapeutic target in inflammatory disease

S Patial, PJ Blackshear - Trends in pharmacological sciences, 2016 - cell.com
… models of immune inflammatory disease. This endogenous anti-inflammatory protein
could serve as the basis for novel approaches to therapy of similar conditions in humans. …

[HTML][HTML] Targeting of NLRP3 inflammasome with gene editing for the amelioration of inflammatory diseases

C Xu, Z Lu, Y Luo, Y Liu, Z Cao, S Shen, H Li… - Nature …, 2018 - nature.com
… acute and chronic inflammatory diseases. Our results … therapy for NLRP3-dependent
inflammatory diseases. Our study also provided an example for treating immune-related diseases