… Thus, targeting the FXII-driven contact system seems to be a promising and safe therapeutic
treatment strategy for patients with thrombotic and inflammatory diseases that warrants …

… chronic inflammatory diseases and summarize data that demonstrate how therapeutic targeting
… suggested that TYK2 could be an interesting drug target in chronic inflammatory disease. …

… DM is a chronic disease characterized by impaired response of target tissues to insulin (insulin
resistance) and/or progressively reduced function of pancreatic β-cells, with consequent …

… This review discusses anti-IL-6 therapy in a variety of candidate inflammatory diseases. …
therapeutic applications. Tocilizumab has been approved for RA, JIA, and Castleman's disease …

… diseases has been included. Overall, this review highlights the therapeutic importance of
targeting … the pathogenesis, symptoms, and complications of inflammatory diseases of the skin. …

… are considered to be angiogenic inflammatory diseases. Several angiogenic … targeted by
several specific approaches that could be therapeutically used to control inflammatory diseases…

… as a new therapeutic strategy [9]. In this review, we focus on the pathological roles of IL-33
in inflammatory diseases and highlight potential strategies to target IL-33/ST2 signalling. …

… of pyroptosis as a therapeutic target in human diseases. Blockade of pyroptosis by compounds
can treat inflammatory disease and pyroptosis activation contributes to cancer therapy. …

… based on their anti-inflammatory properties or on clinical … pathway in these inflammatory
diseases that target specific organs, and … versus attractive therapeutic agents in those diseases. …

Tumor necrosis factor-a (TNF-a) is the first identified member of a large family of cytokines
known to be involved in a wide variety of cellular activities. Discovery of these cytokines has its …