… elevated levels of tumor necrosis factor (TNF)… protein Tat, which is released extracellularly
from infected cells, may induce the production of TNF-α. Tat induced TNF-α mRNA and protein …

… The HIV-1 protein Tat has been shown to be directly and indirectly neurotoxic. Here, … Tat
can, through actions on immune cells, increase neuronal cell death. Tat 1–72 and a mutant Tat 1…

… that the Tat protein of human immunodeficiency virus type 1 (HIV-1) transactivates tumor
necrosis factor alpha and beta (TNFa and TNF,) gene expression in HIV-1-infected and in tat-…

… Tat protein for 10 to 30 min suffices to irreversibly engage the activation of the TLR4 pathway,
leading to the production of tumor necrosis … whether the HIV-1 Tat protein is able to activate …

… This study focused on HIV Tat protein because it plays a important role in the pathogenesis
of HIV infection. Our results confirm that HIV Tat treated monocytes are relatively resistant to …

… The human immunodeficiency virus (HIV) Tat protein has a … It is well known that Tat induces
tumor necrosis factor-related … cells did not take up soluble HIV Tat-86, as T cells did, yet …

… HIV-infected macrophages have been shown to secrete large quantities of inflammatory
cytokines, particularly tumor necrosis factor-a (TNF-a).' TNF is a potent activator of endothelial …

… and how HIV-1 Tat protein, an immunosuppressive viral factor, … We found that treatment of
DCs with whole HIV-1 Tat protein … The induction of PD-L1 on MoDCs by HIV-1 Tat (i) occurred …

… examined whether tumor necrosis factor-alpha (TNF-α) mediates the interaction between Tat
and MA. … Oxidative damage induced by the injection of HIV-1 Tat protein in the rat striatum …

… virus-encoded regulatory protein Tat, which interacts with the specific Tat response (TAR) …
tumor necrosis factor alpha (TNF-a) can replace the requirement for a functional Tat protein. …