… of tau PET tracers. Extensive work remains in order to fully characterize the binding properties
of the tau PET tracers… findings on the most promising tau PET tracers to date, discuss what …

… Recently, several PET tracers have been developed for imaging tau pathology in the …
tracers bind to the β-pleated sheet structure of tau protein fibrils in the same way as amyloid PET …

… Tau PET tracers have enabled in vivo quantification of PHF-tau burden in human brains. …
Therefore, low molecular weight compounds have been used as tau PET tracers [18, 19]. …

… very few reports on imaging agents selectively targeting tau aggregates. In search of [18F]-PET
tracers that possess great binding affinity and selectivity toward tau tangles, we tested …

… Nearly a decade after the introduction of the first potent tau PET tracer, we will … tau PET
tracers bind the tau aggregates formed in AD in the more advanced Braak stages (.IV). Tracer …

… imaging of tau aggregates in chronic traumatic encephalopathy? Will we need more advanced
tau tracers to image … Will novel tau tracers be able to cover earlier tau stages in AD? The …

… To our knowledge, at least seven tau pathology PET tracers have been developed and used
in clinical studies: C-11 PBB3, F-18 THK-523, F-18 THK-5105, F-18 THK-5117, F-18 T808, F…

… Despite the challenges inherent in imaging tau [22, 23], … first PET tracer developed to target
tau but due to lack of specificity and selectivity in vivo [24], a new set of tau PET tracers was …

… Discovery and preclinical characterization of [(18)F]PI-2620, a next-generation tau PET
tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies. Eur J …

… Abnormal aggregation of tau proteins is one of the main pathologies … on the second-generation
of Tau PET tracers is provided. The … tau tracers to advance tau PET imaging in the clinic. …