… We show here that Tax, in the absence of NF-κB signaling, can activate activator protein-1
to promote cellular proliferation and survival. Tax is shown to activate activator protein-1 …

… Cellular proliferation is stimulated by direct targeting of the … Among oncoproteins found
in retroviruses, Tax proteins of the delta subgroup are unique since they have no homology to …

… , its role in binding to various host cellular proteins involved in tumorigenesis has not been
… the Tax-associated proteins and their functions in cells using several approaches. Tax eluted …

… proliferation of synovial cells, and their expression is NF-KB dependent. We have further
demonstrated that treatment of synovial cells with 250 pM Tax protein … synovial cell proliferation …

… -cells and to induce tumors in transgenic mice. In this article we discuss these effects of Tax
… the HTLV-1 carriers' infected T-cells and so is the level of Tax protein, although rare infected …

… -2 cells that expressed Tax protein, and the results are summarized in Table1. CTLL-2 and
CTLL-2/M22 cells … Since Tax induced IL-2-independent proliferation of CTLL-2 cells, we next …

… between Tax-1 and cellular proteins play a key role in HTLV-induced cell proliferation and
… Tax-1 PBM and some cellular proteins facilitates in vivo viral survival, stimulates abnormal …

… Tax-expressing cells, cyclin-D3 protein … Tax with cyclin D is responsible for the activation of
cyclin D-cdk and the subsequential induction of cellular proliferation, we tested whether a Tax …

… and Tax stimulate cell proliferation are complex and fascinating. In fact, HBZ and Tax have
… Among viral proteins, Tax is a major target of cytotoxic T-cells (CTLs) [47]. It is well known …

… proteins, Tax, Rex, and p2lX, between the env gene and the 3' long terminal repeat. Tax is a
nuclear protein … but also a number of cellular genes involved in cell proliferation control (23): …