[HTML][HTML] Technical considerations for the use of CRISPR/Cas9 in hematology research

MC Gundry, DP Dever, D Yudovich, DE Bauer… - Experimental …, 2017 - Elsevier
… of three recent CRISPR/Cas9 methods in hematology: gene disruption, gene targeting,
and saturating mutagenesis. We also summarize the technical considerations and advice …

CRISPR/Cas9 gene-editing: Research technologies, clinical applications and ethical considerations

F Memi, A Ntokou, I Papangeli - Seminars in perinatology, 2018 - Elsevier
… outstanding technical challenges and ethical considerations will … Here, we review
CRISPR/Cas9 technology and discuss its … considerations surrounding the use of CRISPR gene …

[HTML][HTML] CRISPR/Cas9 and mitochondrial gene replacement therapy: promising techniques and ethical considerations

S Fogleman, C Santana, C Bishop, A Miller… - American journal of …, 2016 - ncbi.nlm.nih.gov
… therapy, and CRISPR/Cas9. Mitochondrial replacement therapy … The leading-edge
CRISPR/Cas9 technology exploits the … is important that the ethical considerations herein emerge …

CRISPR/Cas9 genome editing–new and old ethical issues arising from a revolutionary technology

M Baumann - NanoEthics, 2016 - Springer
CRISPR/Cas9 technology was used to modify human embryos for the first time. This article
… knowledge about the technical and scientific state of the art, economic considerations, the …

CRISPRcas9: A history of its discovery and ethical considerations of its use in genome editing

I Gostimskaya - Biochemistry (Moscow), 2022 - Springer
… However, despite the apparent advantages of the CRISPRCas9 system, numerous
ethical and technical difficulties stand in the way of researchers who dream of curing life-threatening …

CRISPR-Cas9 system: opportunities and concerns

SK Vasiliou, EP Diamandis, GM Church… - Clinical …, 2016 - academic.oup.com
… : The main technological improvements to the CRISPR-Cas9 … Some of the most innovative
CRISPR-Cas9 technology … But risk–benefit considerations may indicate its use in certain …

CRISPR/Cas-mediated base editing: technical considerations and practical applications

KA Molla, Y Yang - Trends in biotechnology, 2019 - cell.com
Genome editing with CRISPR/Cas has rapidly gained popularity. Base editing, a new
CRISPR/Cas-based approach, can precisely convert one nucleotide to another in DNA or RNA …

[HTML][HTML] Principles of CRISPR-Cas9 technology: advancements in genome editing and emerging trends in drug delivery

AAA Aljabali, M El-Tanani, MM Tambuwala - Journal of Drug Delivery …, 2024 - Elsevier
CRISPR-Cas9 through nanomaterials, while also addressing ethical and regulatory
considerations. In … Moreover, the formidable technical hurdle of efficiently delivering nanomaterials …

Bioethical issues in genome editing by CRISPR-Cas9 technology

FB Ayanoğlu, AE Elçin, YM Elçin - Turkish Journal of Biology, 2020 - journals.tubitak.gov.tr
… potential effects of CRISPRCas9 in other areas should not be forgotten. CRISPRCas9 is
not … Interactions with other organisms and the environment, such as the consideration of the …

CRISPR-Cas and its wide-ranging applications: From human genome editing to environmental implications, technical limitations, hazards and bioethical issues

R Piergentili, A Del Rio, F Signore, F Umani Ronchi… - Cells, 2021 - mdpi.com
… , we recall here briefly a few examples of CRISPR/Cas9 used as a tool to treat human diseases.
… This work [55] suggests the potential use of CRISPR/Cas9 as a therapeutic strategy for …