Teichoic acid biosynthesis as an antibiotic target

LW Pasquina, JP Santa Maria, S Walker - Current opinion in microbiology, 2013 - Elsevier
… Lipoteichoic acids (LTAs) and wall teichoic acids (WTAs) are cell wall polymers that play …
Here we describe recent progress toward the discovery of teichoic acid biosynthesis

[HTML][HTML] Wall teichoic acid function, biosynthesis, and inhibition

JG Swoboda, J Campbell, TC Meredith… - … : a European journal of …, 2010 - ncbi.nlm.nih.gov
… have speculated that their reporter assay can be used in a high-throughput screen to
identify compounds that target either the cell wall or wall teichoic acid biosynthetic pathways. …

The structure, biosynthesis and function of teichoic acid

AR Archibald - Advances in microbial physiology, 1974 - Elsevier
Teichoic acids are phosphorylated polymers which occur in probably all Gram-positive …
Several different types of teichoic acid have been encountered and their structure, biosynthesis

Teichoic and teichuronic acids: biosynthesis, assembly, and location

JB Ward - Microbiological reviews, 1981 - Am Soc Microbiol
… the biosynthesis of both teichoic acid and certain teichuronic … LOCATION OF TEICHOIC
ACIDS Initially, teichoic acids were … with cold dilute trichloroacetic acid. However, particularly …

Wall teichoic acids of gram-positive bacteria

S Brown, JP Santa Maria Jr… - Annual review of …, 2013 - annualreviews.org
… Brown S, Zhang YH, Walker S, 2008; A revised pathway proposed for Staphylococcus
aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps. …

Structure, biosynthesis, and function of teichoic acids

J Baddiley - Accounts of Chemical Research, 1970 - ACS Publications
… , bacitracin has no significant inhibitory effect on teichoic acid biosynthesis.24 An especially
interesting feature of teichoic acid biosynthesis arises in the case of the glycerol phosphate…

Taking aim at wall teichoic acid synthesis: new biology and new leads for antibiotics

EWC Sewell, ED Brown - The Journal of antibiotics, 2014 - nature.com
… substrate analogs for teichoic acid biosynthetic intermediates has … teichoic acid biosynthetic
proteins. Cumulatively, this work led to the definition of both the structures and biosynthetic

Discovery of a Small Molecule that Blocks Wall Teichoic Acid Biosynthesis in Staphylococcus aureus

JG Swoboda, TC Meredith, J Campbell… - ACS chemical …, 2009 - ACS Publications
… genes in many of the biosynthetic pathways are conditionally essential: … of wall teichoic acid
(WTA) biosynthesis in Staphylococcus … the completion of WTA biosynthesis once it has been …

Late-Stage Polyribitol Phosphate Wall Teichoic Acid Biosynthesis in Staphylococcus aureus

TC Meredith, JG Swoboda, S Walker - Journal of bacteriology, 2008 - Am Soc Microbiol
… distinct polyribitol-containing teichoic acid that we designate K-WTA. The biosynthesis of
K-WTA … The demonstration of regulated wall teichoic acid biosynthesis has implications for cell …

Insights into teichoic acid biosynthesis by Bifidobacterium bifidum PRL2010

A Colagiorgi, F Turroni, L Mancabelli… - FEMS microbiology …, 2015 - academic.oup.com
Teichoic acids (TAs) have previously been shown to play an important role in modulating …
for TA biosynthesis, suggesting that bifidobacteria contain both wall TAs and lipoteichoic acids. …