… and response to temozolomide in 44 patients with pituitary carcinomas or aggressive
pituitary tumours reported in the literature. The results suggest that temozolomide should be …

… treatment of surgery, … pituitary carcinoma treated with temozolomide. In June, 1997, a
72-year-old man with known microprolactinoma, successfully controlled with D2-agonist treatment (…

… Recently, a limited number of aggressive pituitary adenomas and carcinomas resistant to
conventional treatment have been reported to respond to temozolomide (TMZ) therapy (Table 1…

… the efficacy of temozolomide treatment for some aggressive pituitary tumors or carcinomas;
however, the study reveals MGMT status as a poor predictor of treatment outcome that should …

… is effective in some patients with progressive pituitary adenoma or carcinoma. We …
Temozolomide because of aggressive pituitary adenoma or carcinoma resistant to standard …

… efficacy of temozolomide (TMZ) treatment for aggressive pituitary tumours including pituitary
… change in the management of these challenging tumours. Prior to the first TMZ cases …

… to temozolomide in pituitary tumours. Materials and methods This paper will review the current
literature on temozolomide and pituitary tumours … the MGMT status in this tumour group. A …

Objectives Only few retrospective studies have reported an efficacy rate of temozolomide (TMZ)
in pituitary tumors (PT), all around 50%. However, the long-term survival of treated …

… therapy or cytotoxic chemotherapy.We report two cases of pituitary carcinomas that
responded to temozolomide… associated with temozolomide treatment. If proven effective, this …

… with the use of temozolomide in six patients with different variants of aggressive pituitary
tumors. … We use the denomination pituitary carcinoma when extrapituitary presence of tumor (…