Effect of tumor-treating fields plus maintenance temozolomide vs maintenance temozolomide alone on survival in patients with glioblastoma: a randomized clinical …

R Stupp, S Taillibert, A Kanner, W Read, DM Steinberg… - Jama, 2017 - jamanetwork.com
… The following factors were associated with longer overall survival: TTFields plus temozolomide
treatment (HR, 0.63; 95% CI, 0.53-0.76; P < .001), female sex (HR, 0.76, 95% CI, 0.63-…

Temozolomide treatment can improve overall survival in aggressive pituitary tumors and pituitary carcinomas

H Lasolle, C Cortet, F Castinetti, L Cloix… - European Journal of …, 2017 - academic.oup.com
… The median follow-up after the end of treatment was 16 months (0–72). Overall survival was
… (0–57) after the end of TMZ treatment, five in whom TMZ was reinitiated without success. …

Maintenance therapy with tumor-treating fields plus temozolomide vs temozolomide alone for glioblastoma: a randomized clinical trial

R Stupp, S Taillibert, AA Kanner, S Kesari… - Jama, 2015 - jamanetwork.com
temozolomide alone had a median progression-free survival of … TTFields plus temozolomide
had a median overall survival of … months in those who received temozolomide alone (as per …

Temozolomide in the treatment of recurrent malignant glioma

SM Chang, P Theodosopoulos, K Lamborn, M Malec… - Cancer, 2004 - Wiley Online Library
… Despite maximal safe surgical debulking and radiation treatment, overall survival (OS) for
the average patient remains poor.1-5 Several chemotherapeutic agents, most notably the …

Temozolomide for the treatment of metastatic melanoma: a systematic review

I Quirt, S Verma, T Petrella, K Bak, M Charette - The oncologist, 2007 - academic.oup.com
… efficacy for response rates and overall survival; however, no … -agent temozolomide with
temozolomide combined with … the combination treatment arm, but no difference in overall survival

Glioblastoma survival in the United States before and during the temozolomide era

DR Johnson, BP O'Neill - Journal of neuro-oncology, 2012 - Springer
overall survival of patients confirmed to be treated with … survival in the second period (log-rank
P < 0.0001). Table 2 contains median survival, 24-month survival, and 36-month survival

Glioblastoma treatment with temozolomide and bevacizumab and overall survival in a rural tertiary healthcare practice

TC Carter, R Medina-Flores… - BioMed research …, 2018 - Wiley Online Library
… significant increase in overall survival when compared with no treatment in this study. In a
… , a gain in overall survival with use of bevacizumab compared with use of other treatment for …

MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis based on a …

S Brandner, A McAleenan, C Kelly, F Spiga… - Neuro …, 2021 - academic.oup.com
… all patients were treated with temozolomide. We focused on overall survival only, so are
unable to draw conclusions about using techniques to predict progression-free survival. The …

Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States

SA Grossman, X Ye, S Piantadosi, S Desideri… - Clinical cancer …, 2010 - AACR
… and temozolomide (RT + TMZ) in newly diagnosed glioblastoma using overall survival as the
… Organization for Research and Treatment of Cancer (EORTC) survival data that resulted in …

Temozolomide: therapeutic limitations in the treatment of adult high-grade gliomas

MC Chamberlain - Expert review of neurotherapeutics, 2010 - Taylor & Francis
… This study indicates that the addition of TMZ to radiotherapy improves overall survival by
2.5 months, a modest and incremental improvement. Importantly, in a separate analysis of all …