… by which the Lin-14p temporal gradient is generated. We find that temporal regulation of Lit-r-…
multiple conserved elements complementary to the /in-4 RNAs. These data suggest that the …

… explore how the lin-14 temporal switch is regulated by these … temporal expression pattern
of lin-14 in mutants and wild type, we find that lin-28 and lin-4 act antagonistically to regulate lin…

… temporal regulation of LIN-14 abundance is required for the wild-type sequence of temporal
… Therefore, those sequences that are required for lin-14 temporal regulation should be …

… temporal development and reporter activity in animals where lin-4 is modulated, we have
demonstrated that lin-4 … a cell autonomous component of temporal regulation in C. elegans. …

… We did not detect lin-4 RNA in these species. We found that let-7 temporal regulation is also
… The let-7 regulatory RNA may control late temporal transitions during development across …

… the expression of mouse Lin-28 appears to be strictly temporally regulated, as is its C.
elegans orthologue. The temporal pattern is indicated by Lin-28's overall down-regulation in the …

… Mlin-41 is down-regulated during mid-embryogenesis at the time when mouse let-7c and mir…
up-regulated. Our results suggest that mammalian lin-41 is temporally regulated by miRNAs …

… understanding of the temporal regulation of development. … temporal regulation. Much is
known about the biogenesis and function of miRNAs, but how these processes are temporally …

… regulation during epithelial differentiation. Here, we focus on the regulation of the gene lin-26…
lin-26 expression starts in early embryos and remains on throughout development, in many …

… structure, diverse temporal and spatial expression … LIN-42 in a unique situation to regulate
diverse pathways. Such ability suggests that LIN-42 uses a common mechanism to regulate …