Tetraploid complementation proves pluripotency of induced pluripotent stem cells derived from adipose tissue

C Zhou, X Cai, Y Fu, X Wei, N Fu, J Xie… - Cell Proliferation, 2015 - Wiley Online Library
pluripotency of induced pluripotent stem (iPS) cells has been displayed after producing adult
mice, in tetraploid complementation … fully pluripotent cells which function as embryonic stem

[HTML][HTML] Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation

L Kang, T Wu, Y Tao, Y Yuan, J He, Y Zhang, T Luo… - Cell research, 2011 - nature.com
… also be fully pluripotent, as viable mice could be generated from three-factor iPSCs
autonomously via tetraploid complementation and moreover, our data indicate that the pluripotency

Production of mice using iPS cells and tetraploid complementation

XY Zhao, Z Lv, W Li, F Zeng, Q Zhou - Nature Protocols, 2010 - nature.com
Induced pluripotent stem cells (iPSCs) are considered to be … live animals through the
tetraploid complementation assay. Our … pluripotent iPS cells tested by tetraploid complementation

iPS cells produce viable mice through tetraploid complementation

X Zhao, W Li, Z Lv, L Liu, M Tong, T Hai, J Hao, C Guo… - nature, 2009 - nature.com
… Since the initial description of induced pluripotent stem (iPS) cells created by forced
expression of four transcription factors in mouse fibroblasts, the technique has been used to …

[HTML][HTML] Mice generated from tetraploid complementation competent iPS cells show similar developmental features as those from ES cells but are prone to …

M Tong, Z Lv, L Liu, H Zhu, QY Zheng, XY Zhao, W Li… - Cell research, 2011 - nature.com
… Ever since the creation of induced pluripotent cells (iPSCs) … iPS cells are equivalent to
embryonic stem cells (ESCs) in … full-term mice via the tetraploid complementation method 3,4,…

[HTML][HTML] Pluripotency of induced pluripotent stem cells

L Kang, S Gao - Journal of animal science and biotechnology, 2012 - Springer
… demonstrated full pluripotency of mouse iPS cells by tetraploid complementation, indicating
… be produced from iPS cells via tetraploid complementation, even with extensive efforts [21]. …

Adult mice generated from induced pluripotent stem cells

MJ Boland, JL Hazen, KL Nazor, AR Rodriguez… - Nature, 2009 - nature.com
… lines can generate adult mice in tetraploid complementation assays, we designed a genetic
… To prioritize the iMZ cell lines for tetraploid complementation assays, we assessed lines for …

[HTML][HTML] iPS cells can support full-term development of tetraploid blastocyst-complemented embryos

L Kang, J Wang, Y Zhang, Z Kou, S Gao - Cell stem cell, 2009 - cell.com
induced pluripotent stem cells (iPSCs) can autonomously generate full-term mice via tetraploid
blastocysts complementation. … fully pluripotent, resembling normal embryonic stem cells (…

Rat embryonic stem cells produce fertile offspring through tetraploid complementation

TD Li, GH Feng, YF Li, M Wang… - Proceedings of the …, 2017 - National Acad Sciences
… -specific differences in its regulation and maintenance, which have implications for the
derivation and application of naïve pluripotent stem cells in other species including human. …

[HTML][HTML] iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation

W Li, X Zhao, H Wan, Y Zhang, L Liu, Z Lv, XJ Wang… - Cell research, 2011 - nature.com
… Due to its ethical acceptability and technical feasibility, production of induced pluripotent
stem (iPS) cells from differentiated somatic cells by exogenous expression of several key …