… chimaeric mice with germline transmission by blastocyst injection. Three of these lines
produced viable, live-born offspring by tetraploid complementation. We infected mouse embryonic …

… of mice that are entirely derived from ES cells by either nuclear cloning … tetraploid embryo
complementation. In addition, our results demonstrate that tetraploid embryo complementation …

… mice and offspring (d) have mixed coat colors, whereas all-iPS mice from tetraploid
complementation (black mouse … This iPS black mouse produced viable offspring when mated with …

… of tumorigenecity in the iPS-chimeric mice and also might hinder the clinical … , as viable
mice could be generated from three-factor iPSCs autonomously via tetraploid complementation …

… frequency at which F1 ES cells gave rise to viable offspring. After injection with the wild-type
ES cell line Art4.12, 10.4% of tetraploid blastocysts gave rise to viable mice (n = 77 viable …

… and mice could be derived solely from R1 ES cells by aggregating them with tetraploid …
ES cell-derived embryos because hprt knockout mice are viable and fertile [12]. E14TG2a-derived …

… of viable and fertile adults. Thus, the range of developmental potentials of tetraploid embryos
… and experimental utility of tetraploid mammals, in particular the mouse. Developmental …

… animals in tetraploid complementation assay depends on the genetic heterozygosity.
Characterized F1-hybrid ES cells combined with tetraploid embryos can give rise to viable and …

… mouse strains. This protocol describes the procedures necessary for the production of mouse
chimeras by tetraploid complementation … Moreover, it is possible to derive viable and fertile …

… for the production of viable ES cell-derived mice by tetraploid embryo complementation. …
used in our laboratory for the production of viable ES cell-derived mice by tetraploid embryo …