Increased Th2 activity and diminished skin barrier function cooperate in allergic skin inflammation

S Sehra, P Krishnamurthy, B Koh… - European journal of …, 2016 - Wiley Online Library
inflammatory infiltrates as compared with Stat6VT mice. Our study suggests that skin barrier
defects and altered Th2skin inflammation, similar to effects observed in patients with AD. …

[HTML][HTML] TH1 and TH2 Lymphocyte development and regulation of TH Cell–mediated immune responses of the skin

T Biedermann, M Röcken, JM Carballido - Journal of Investigative …, 2004 - Elsevier
inflammatory responses after challenge (CHSR), mice treated with IL-4 show only little
hapten-specific disease activity … TH1 and TH2 cell–mediated skin inflammation therefore control …

Role of Th17 cells in skin inflammation of allergic contact dermatits

M Peiser - Journal of Immunology Research, 2013 - Wiley Online Library
… of T helper(h) 1 and Th2 cells on the bottom of many inflammatory diseases, Th17 cells were
… In ACD, the activity of cytotoxic T cells becomes evident in the appearance of skin lesions, …

[HTML][HTML] Th2 cytokines and atopic dermatitis

EB Brandt, U Sivaprasad - Journal of clinical & cellular immunology, 2011 - ncbi.nlm.nih.gov
… lost, increased skin inflammation dominated by eosinophils … pro-inflammatory cytokines
(TNF-α or IL-1α) and Th2 cytokines (… the membrane fraction having the greatest activity [37]. TSLP …

TH1/TH2 cytokines and inflammatory cells in skin biopsy specimens from patients with chronic idiopathic urticaria: comparison with the allergen-induced late-phase …

S Ying, Y Kikuchi, Q Meng, AB Kay… - Journal of Allergy and …, 2002 - Elsevier
… compare skin biopsy specimens from patients with CIU and the allergen-induced skin LPR …
The profile of inflammatory cell infiltration in the allergen-induced skin LPR was similar to that …

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor

T Satoh, R Moroi, K Aritake, Y Urade… - The Journal of …, 2006 - journals.aai.org
… role in chronic allergic skin inflammation. CRTH2 may … , exhibits a wide range of biological
activities including vasodilatation, … of PGDS induces Th2-dominated lung inflammation with …

[HTML][HTML] Preferential binding of Staphylococcus aureus to skin sites of Th2-mediated inflammation in a murine model

SH Cho, I Strickland, A Tomkinson, AP Fehringer… - Journal of investigative …, 2001 - Elsevier
skin inflammation were utilized in this study: first, a model of Th1-induced, interferon-γ (IFN-γ)
skin inflammation … model of Th2-induced interleukin-4 (IL-4) mediated skin inflammation in …

IL-2 controls trafficking receptor gene expression and Th2 response for skin and lung inflammation

ST Ju, R Sharma, F Gaskin, SM Fu - Clinical immunology, 2012 - Elsevier
… multi-organ inflammation but only the latter display severe skin and lung inflammation. In …
mice do not display skin inflammation and markedly reduced lung inflammation. In this review, …

Th2‐like cytokine activity in dermatitis herpetiformis

M Caproni, C Feliciani, A Fuligni… - British Journal of …, 1998 - academic.oup.com
… 5; these last two cases were histologically poor in inflammatory cells. In view of these results,
it can … skin, which seem to have a preferential polarization towards the Th2‐like phenotype. …

IL‐31 significantly correlates with disease activity and Th2 cytokine levels in children with atopic dermatitis

U Raap, S Weißmantel, M Gehring… - Pediatric Allergy and …, 2012 - Wiley Online Library
activity, although with no impact on skin inflammation (10). It seems that in humans, the
regulatory process of IL-31 in skin inflammation … , sleeplessness, and Th2 cytokines including IL-4 …