Two distinct types of theca cells in the medaka gonad: Germ cell‐dependent maintenance of cyp19a1expressing theca cells

S Nakamura, H Kurokawa, S Asakawa… - … dynamics: an official …, 2009 - Wiley Online Library
… precursors of theca cells. We also demonstrate that the cyp19a1-expressing theca cells are
… -I (cyp17a1)-expressing theca cells and that the presence of germ cells is essential for the …

Transcription of CYP19A1 is directly regulated by SF-1 in the theca cells of ovary follicles in chicken

J Wang, Y Gong - General and Comparative Endocrinology, 2017 - Elsevier
… of CYP19A1 regulation in chicken remains unknown. Here, we found that CYP19A1 was only
expressed in the theca cell … that CYP19A1 was mainly expressed in theca externa cells of …

The involvement of granulosa cells in the regulation by gonadotropins of Cyp17a1 in theca cells

H Kakuta, T Iguchi, T Sato - in vivo, 2018 - iv.iiarjournals.org
… of E2 and the expression of Cyp17a1 and Cyp19a1 remain high … of granulosa cells in the
regulation of Cyp17a1 in theca cells. … It is known that Cyp17a1 expression in theca cells from …

Diethylstilbestrol administration inhibits theca cell androgen and granulosa cell estrogen production in immature rat ovary

Y Imamichi, T Sekiguchi, T Kitano, T Kajitani… - Scientific reports, 2017 - nature.com
Cyp19a1 expression in cultured granulosa cells. These results indicate that DES inhibits
thecal … of pituitary LH secretion and ovarian Cyp17a1 expression. In addition, DES represses …

… transcriptomic comparison of theca and granulosa cells in chicken and cattle follicles reveals ESR2 as a potential regulator of CYP19A1 expression in the theca cells …

R Jing, L Gu, J Li, Y Gong - … Biochemistry and Physiology Part D: Genomics …, 2018 - Elsevier
… highly associated with CYP19A1 expression in chicken SYFs were … of the transcriptomes of
theca and granulosa cells (TCs and … the expression of CYP19A1 in chicken SYFs theca cells. …

Transcriptional regulation of CYP19A1 expression in chickens: ESR1, ESR2 and NR5A2 form a functional network

Y Guo, L Cheng, X Li, S Tang, X Zhang… - General and Comparative …, 2022 - Elsevier
… , CYP19A1 is expressed in chickens in the theca cells of ovarian follicles, and the mechanism
of CYP19A1 expression … , we first confirmed that CYP19A1 and FOXL2 (Forkheadbox L2) …

[HTML][HTML] … negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17α-hydroxylase/17, 20 lyase) expression

F Taniguchi, JF Couse, KF Rodriguez… - The FASEB journal …, 2007 - ncbi.nlm.nih.gov
… inhibitor (AI) to block CYP19A1-mediated aromatization of C 19 -… The AI employed is reported
to specifically inhibit CYP19A1 … As expected, inhibition of CYP19A1 activity led to a dose-…

CYP19A1 gene expression in patients with polycystic ovarian syndrome

R Panghiyangani, P Soeharso… - Journal of Human …, 2020 - journals.lww.com
… FSH acts in granulosa cells to aromatize the androgens from theca cells into estrogen, via
its action through follicle stimulating hormone receptor (FSHR). In PCOS cases, Asn680Ser …

Distinct Regulation by Steroids of Messenger RNAs for FSHR and CYP19A1 in Bovine Granulosa Cells

W Luo, MC Wiltbank - Biology of reproduction, 2006 - academic.oup.com
… In addition, FSH did produce a slightly greater increase in CYP19A1 expression in cells that
… In conclusion, androgen from thecal cells appears to regulate granulosa cell function by …

The pre‐ovulatory luteinizing hormone surge is followed by down‐regulation of CYP19A1, HSD3B1, and CYP17A1 and chromatin condensation of the …

M Nimz, M Spitschak, R Fürbass… - Molecular reproduction …, 2010 - Wiley Online Library
… granulosa cells in the theca-cell fraction or to marginal expression of this gene by cells of the
theca … was restricted to the theca. So far, it has been shown in other species that RUNX1 is …