Theoretical simulation of temperature distribution in the brain during mild hypothermia treatment for brain injury

L Zhu, C Diao - Medical and Biological Engineering and Computing, 2001 - Springer
… However, when the head surface is cooled during hypothermia treatment, the arterial blood
… Our theoretical simulation also predicts that the thickness of the brain tissue layer with …

A thermoregulation model for hypothermic treatment of neonates

ABCG Silva, J Laszczyk, LC Wrobel, FLB Ribeiro… - Medical Engineering & …, 2016 - Elsevier
… This paper presents a thermoregulation finite element model (FEM) to simulate hypothermia
procedures for the treatment of encephalopathy hypoxic-ischemia (EHI) in neonates, a …

Theoretical evaluations of therapeutic systemic and local cerebral hypothermia

E Keller, R Mudra, C Gugl, M Seule, S Mink… - Journal of neuroscience …, 2009 - Elsevier
treatment applying different cooling devices and to find the optimal brain temperature … model
to simulate cerebral temperature behaviour during induction of therapeutic hypothermia, to …

Modelling hypothermia in patients undergoing surgery

NMW Severens - 2008 - research.tue.nl
… colder periphery, leading to hypothermia. The heat balance … back surgery and deep
hypothermic surgery with circulatory … a mild hypothermia protocol instead of a moderate …

Modeling and simulation of hypothermia effects on cardiac electrical dynamics

Y Belhamadia, J Grenier - PloS one, 2019 - journals.plos.org
… as a therapeutic treatment for … simulations are presented to study the effect of temperature
variations on a regular electrophysiological wave and to investigate the effect of hypothermia

A mathematical model of intracranial pressure dynamics for brain hypothermia treatment

L Gaohua, H Kimura - Journal of theoretical biology, 2006 - Elsevier
simulation results to population-averaged data and clinical evidence of brain hypothermia
treatment… , and to adjust model parameters to simulate pathophysiological states of intracranial …

A thermoregulation model for whole body cooling hypothermia

ABCG Silva, LC Wrobel, FLB Ribeiro - Journal of thermal biology, 2018 - Elsevier
… The simulation of blood cooling for hypothermia treatments using methods applied directly
to the blood vessels, as … The simulations presented in this work reproduce a hypothermic

Targeted brain hypothermia induced by an interstitial cooling device in human neck: theoretical analyses

Y Wang, L Zhu - European journal of applied physiology, 2007 - Springer
… fits the clinically acceptable treatment window of 1–2 h during which brain hypothermia must
be … cooling device is evaluated using a theoretical simulation of the temperature fields in the …

Therapeutic hypothermia induction via an esophageal route—a computer simulation

V Vaicys, A Eason, JD Schieber, EB Kulstad - The American journal of …, 2012 - Elsevier
hypothermia may help increase use of this treatment. We developed a mathematical model
to evaluate the potential to induce mild therapeutic hypothermia … maximum theoretical heat …

A mathematical model of respiratory and biothermal dynamics in brain hypothermia treatment

L Gaohua, H Kimura - IEEE Transactions on Biomedical …, 2008 - ieeexplore.ieee.org
… curves is depicted in all CO2 levels, while taking into account the difference of the initial
values of minute ventilation between the theoretical simulation and the clinical experiments. …