Therapeutic pathways of adult stem cell repair

AE Ting, RW Mays, MR Frey, W Van't Hof… - Critical reviews in …, 2008 - Elsevier
… stroke surgery suggest an … repairing injured tissues has the potential for the development
of an entire new class of products, as both cellular therapeutics or as protein therapeutic agents

Scar–free healing: from embryonic mechanisms to adult therapeutic intervention

MWJ Ferguson, S O'Kane - Philosophical Transactions of …, 2004 - royalsocietypublishing.org
… We also demonstrate that both repair with scarring and regeneration can occur within …
therapeutic agent to improve scarring need to be administered early, ie around the time of surgery

[HTML][HTML] Current and future medical therapeutic strategies for the functional repair of spinal cord injury

T Yılmaz, E Kaptanoğlu - World journal of orthopedics, 2015 - ncbi.nlm.nih.gov
therapy, early surgery, aggressive volume resuscitation and blood pressure elevation to
maximize spinal cord perfusion, early rehabilitation and cellular therapies. … timing for surgery in …

Instructional course lectures, the American Academy of Orthopaedic Surgeons-growth factors as therapeutic agents

SB Trippel, RD Coutts, TA Einhorn, GR Mundy… - JBJS, 1996 - journals.lww.com
… The availability of therapeutic agents that enhance skeletal growth raises several … repair
of intramembranous bone defects, but its therapeutic potential in endochondral fracture repair

DNA repair proteins as molecular targets for cancer therapeutics

MR Kelley, ML Fishel - … Chemistry-Anti-Cancer Agents), 2008 - ingentaconnect.com
… The major DNA repair pathways … NHEJ) repair. While all pathways will be discussed, the
main focus of this review will be on BER and direct repair as pathways with rationale therapeutic

Neural stem cells as therapeutic agents for age‐related brain repair

GM Bernal, DA Peterson - Aging cell, 2004 - Wiley Online Library
… stem cells could be used to repair the brain by repopulating … of using neural stem cells to
repair the aged brain. This review … therapeutic strategies using neural stem cells for repair of the …

The emerging role of DNA repair proteins as predictive, prognostic and therapeutic targets in cancer

S Madhusudan, MR Middleton - Cancer treatment reviews, 2005 - Elsevier
… Prognostic factors are measurements available at the time of diagnosis or surgery that are …
expression has highlighted their potential as therapeutic agents. In a recently published study, …

Wound healing trajectories as predictors of effectiveness of therapeutic agents

MC Robson, DP Hill, ME Woodske… - … of Surgery, 2000 - jamanetwork.com
… One problem in the clinical trials to date attempting to discover such therapeutic agents
has been trial design, including the methodology and determination of end points. As yet, …

Effect of tyrosine kinase inhibitors on wound healing and tissue repair: implications for surgery in cancer patients

DR Shah, S Dholakia, RR Shah - Drug safety, 2014 - Springer
… of sunitinib or sorafenib therapy may actually be risky in terms … that following discontinuation
of TKI therapy in 36 patients with … of TKI therapy 2 weeks before surgery, following a median …

The future of cell therapies and brain repair: P arkinson's disease leads the way

GH Petit, TT Olsson, P Brundin - Neuropathology and applied …, 2014 - Wiley Online Library
… up to 18 years after transplantation surgery in patients with … exceeds placebo effects
associated with surgery. Second, we … on the overall future of cell therapy in Parkinson's disease. …