Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance
M Creixell, NA Peppas - Nano today, 2012 - Elsevier
… by which cells become multidrug resistant (MDR): by … in overcoming resistance of cancer
cells than co-treatment of cancer … -delivery systems in overcoming multidrug cancer resistance. …
cells than co-treatment of cancer … -delivery systems in overcoming multidrug cancer resistance. …
Mechanisms of tumor cell resistance to the current targeted-therapy agents
… Crosstalk between several intracellular signaling pathways is one of the major reasons
for acquired resistance to targeted-therapy agents [139]. BCR and receptor tyrosine kinase-like …
for acquired resistance to targeted-therapy agents [139]. BCR and receptor tyrosine kinase-like …
Drug resistance in cancer–searching for mechanisms, markers and therapeutic agents
R O'Connor, M Clynes, P Dowling… - Expert opinion on …, 2007 - Taylor & Francis
… these agents on normal cells and from resistance – inherent or acquired – to therapeutic
agents… Combination chemotherapy was devised to overcome resistance, by treating with agents …
agents… Combination chemotherapy was devised to overcome resistance, by treating with agents …
Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti‐cancer therapeutic agents
RS Kerbel - Bioessays, 1991 - Wiley Online Library
… Delivery of novel therapeutic agents in tumors: physiological barriers and rtrategier. JNCI 81,
570-576… Vascular and interstitial barriers to delivery of therapeutic agents in tumors. Concer …
570-576… Vascular and interstitial barriers to delivery of therapeutic agents in tumors. Concer …
PROTACs as potential therapeutic agents for cancer drug resistance
X Sun, Y Rao - Biochemistry, 2019 - ACS Publications
… factor that limits the efficacy of a number of anticancer agents. … MCL1 for breast cancer to
overcome clinical resistance. … the focus of discovering novel therapeutic agents against the ABL …
overcome clinical resistance. … the focus of discovering novel therapeutic agents against the ABL …
A recent development of new therapeutic agents and novel drug targets for cancer treatment
ZD Kifle, M Tadele, E Alemu, T Gedamu… - SAGE open …, 2021 - journals.sagepub.com
… cancer leads to the distinguishing of several potential therapeutic agents for can cancer …
The key causes for cancer therapy failure are multidrug resistance, which happened at the …
The key causes for cancer therapy failure are multidrug resistance, which happened at the …
Novel and emerging targeted-based cancer therapy agents and methods
M Hojjat-Farsangi - Tumor Biology, 2015 - Springer
… resistance to different therapeutic agents. Overexpression of miR-1, miR-125a, miR-150, and
miR-425 in glioblastoma increased the resistance of … preventing therapeutic resistance [56]. …
miR-425 in glioblastoma increased the resistance of … preventing therapeutic resistance [56]. …
Significant role of MUC1 in development of resistance to currently existing anti-cancer therapeutic agents
L Farahmand, P Merikhian, N Jalili… - Current Cancer Drug …, 2018 - ingentaconnect.com
… In this review, we briefly describe the role of MUC1 proto-oncogene in cancer cell’s survival,
… which MUC1 induce resistance to various currently existing therapeutic agents in market …
… which MUC1 induce resistance to various currently existing therapeutic agents in market …
Therapeutic agents triggering nonapoptotic cancer cell death
A Kornienko, V Mathieu, SK Rastogi… - Journal of medicinal …, 2013 - ACS Publications
… These novel anticancer agents are critically discussed by the authors, and therefore, the …
opportunities to combat cancers resistant to the established proapoptotic therapeutic agents. …
opportunities to combat cancers resistant to the established proapoptotic therapeutic agents. …
DNA methylation-driven EMT is a common mechanism of resistance to various therapeutic agents in cancer
… resistance to cancer therapies, we from literature identified treatment-naïve epithelial cancer
… lines) that were rendered resistant to a cancer treatment (hereafter referred to as treatment-…
… lines) that were rendered resistant to a cancer treatment (hereafter referred to as treatment-…
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