MicroRNAs in disease and potential therapeutic applications

HS Soifer, JJ Rossi, P Sætrom - Molecular therapy, 2007 - cell.com
… This review summarizes miRNA biogenesis and biology, explores the potential roles miRNAs
… , and suggests some therapeutic applications for restoring or inhibiting miRNA function. …

The prognostic and therapeutic application of microRNAs in breast cancer: Tissue and circulating microRNAs

A Bahrami, A Aledavood, K Anvari… - Journal of cellular …, 2018 - Wiley Online Library
… 1.4 MiRNAs as therapeutic targets Several approaches have been proposed for possible
application of miRNAs as a therapeutic target in treatment of cancer; (1) introduction of miRNA

MicroRNAs as therapeutic targets and their potential applications in cancer therapy

WCS Cho - Expert opinion on therapeutic targets, 2012 - Taylor & Francis
… the latest discovery of miRNAs acting as oncogenes and … the potential applications of miRNA
regulations in cancer therapy. … miRNAs and restoring tumor-suppressive miRNAs for cancer …

Clinical applications for microRNAs in cancer

SP Nana‐Sinkam, CM Croce - Clinical Pharmacology & …, 2013 - Wiley Online Library
… Herein, we provide a broad perspective on the current application of miRNAs as cancer
therapeutics, with a focus on the challenges of translating small-molecule biology to the clinic. …

[PDF][PDF] MicroRNAs and future therapeutic applications in cancer

P Casalini, MV Iorio - J BUON, 2009 - researchgate.net
… of a possible use in therapy. Here we review our current knowledge about the involvement
of microRNAs in cancer, and their potential as diagnostic, prognostic and therapeutic tools. …

Pathogenetic and therapeutic applications of microRNAs in major depressive disorder

Y Dwivedi - Progress in Neuro-Psychopharmacology and …, 2016 - Elsevier
… that determination of miRNAs in blood can be used as possible diagnostic and therapeutic
tool. … and the role of miRNAs in possible etiopathogenesis and therapeutic implications in the …

The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia

JN Gong, J Yu, HS Lin, XH Zhang, XL Yin… - Cell Death & …, 2014 - nature.com
… Recently, miRNAs have gained considerable attention as therapeutic targets in various
diseases. Several strategies have been developed to restore the function of the miRNAs that are …

The diagnosis, prognosis, and therapeutic application of MicroRNAs in haematological malignancies

X Li, H Zhong - Hematology, 2016 - Taylor & Francis
… clinical aspect of miRNAs is their application in targeted therapy. Because miRNAs can
function as both oncogenes and tumour suppressors, their therapeutic directions can be divided …

microRNA‐based diagnostic and therapeutic applications in cancer medicine

LF Sempere, AS Azmi, A Moore - Wiley Interdisciplinary …, 2021 - Wiley Online Library
microRNAs in tissue and bodily fluids, identified the diagnostic, prognostic, and/or predictive
value of individual microRNAs or microRNA … roles of specific microRNAs, and developed a …

MicroRNAs in common diseases and potential therapeutic applications

LM Tsai, D Yu - Clinical and Experimental Pharmacology and …, 2010 - Wiley Online Library
… , miRNA functions primarily in animals. Therefore, the scope of the present review is limited
to a discussion of miRNA… but succinct summary of the role of miRNAs in disease and therapy. …