A new therapeutic approach for the treatment of sepsis

AB Iskit, MO Guc - Medical hypotheses, 2004 - Elsevier
therapeutic modality, the unrelenting hypotension which is the hallmark of patients dying from
septic shock, has dominated all therapeutic … the first step of the sepsis cascade which might …

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

RS Hotchkiss, G Monneret, D Payen - The Lancet infectious diseases, 2013 - thelancet.com
… that occurs in sepsis, and explain why many previous sepsis trials which were … use in sepsis.
We hypothesise that immunoadjuvant therapy represents the next major advance in sepsis. …

Is neuroimmunomodulation a future therapeutic approach for sepsis?

V Kumar, A Sharma - International immunopharmacology, 2010 - Elsevier
sepsis. Therefore pharmacologic stimulation of vagus nerve to release Ach may prove better
therapeutic approach to treat bacterial sepsis. … response responsible for sepsis by binding to …

Therapeutic approaches to innate immunity: severe sepsis and septic shock

E Lolis, R Bucala - Nature reviews Drug discovery, 2003 - nature.com
… Severe sepsis leading to shock is the principal cause of death in … therapeutic development.
This article discusses selected pathophysiological mechanisms that might yield to therapeutic

Sepsis and septic shock: New definitions, new diagnostic and therapeutic approaches

S Esposito, G De Simone, G Boccia, F De Caro… - Journal of global …, 2017 - Elsevier
… Despite advances in management, sepsis and septic shock still … and therapeutic approaches
of sepsis and septic shock. … and to more aggressive therapeutic approach, including earlier …

New therapeutic approaches in sepsis: a critical review

LA Eidelman, R Pizov, CL Sprung - Intensive Care Medicine, 1995 - Springer
… Antibodies against endotoxin should be helpful in Gram-negative sepsis, while therapies
aimed at mediators should be helpful in both Gram-negative and Gram-positive sepsis …

[HTML][HTML] The endothelial glycocalyx: new diagnostic and therapeutic approaches in sepsis

L Martin, P Koczera, E Zechendorf… - BioMed research …, 2016 - hindawi.com
… and sepsis severity. In this review, we highlight the crucial role of the glycocalyx in sepsis
as a … serving as hopeful therapeutic targets in sepsis-associated multiple organ failures. …

[HTML][HTML] HDL in sepsis–risk factor and therapeutic approach

EE Morin, L Guo, A Schwendeman, XA Li - Frontiers in pharmacology, 2015 - frontiersin.org
… may present a novel approach for sepsis therapy. Emerging evidence suggests that High…
sepsis and summarize the efforts of using synthetic HDL (sHDL) as a potential therapy for sepsis

[HTML][HTML] Sepsis-induced AKI: From pathogenesis to therapeutic approaches

FF He, YM Wang, YY Chen, W Huang, ZQ Li… - Frontiers in …, 2022 - frontiersin.org
therapeutic effects in sepsis-induced AKI. Hence, understanding the pathophysiology of
sepsis-induced AKI may help to develop novel therapeutics … new therapeutic approach for sepsis

Sepsis and coronavirus disease 2019: common features and anti-inflammatory therapeutic approaches

J Beltran-Garcia, R Osca-Verdegal… - Critical care …, 2020 - journals.lww.com
therapies). Here, because the potential use of anti-inflammatory therapies in the treatment
of COVID-19 patients, we revisited the previous use of these therapies in sepsis settings. …