… various potential therapies of sepsis and septic … therapeutic approaches, and the use of
well-designed clinical trials (3). Roger Bone likened the search for an effective therapy of sepsis …

… new therapeutic targets. Clinical research has identified various conventional and new
therapeutic approaches … Current research must determine whether some of these approaches are …

… the positive and negative costimulatory pathways on immune cells and neutralization or
removal of endotoxin may represent viable therapeutic approaches in improving sepsis survival. …

… Animal studies of shock, trauma, and sepsis have confirmed … in an experimental model of
sepsis, trauma, and reperfusion … innovative therapeutic approaches for the treatment of sepsis…

… or clinical symptoms similar to sepsis that require diagnostic … of sepsis has evolved in the
past decades with new therapeutic options of improved antibiotics and more novel approaches (…

… are in an urgent need for a multi-targeting therapeutic approach for sepsis. … sepsis
pathogenesis, lessons learned, and the future therapeutic/early diagnostic approaches to target …

… efficacy of antibiotic therapy and this is a grade 2C recommendation in the latest surviving
sepsis guidelines. Not only can procalcitonin guide when to start or stop antibiotic therapy, but …

… sepsis often becomes a syndrome of last resort rather than a diagnosis until proven otherwise.
Even when sepsis is timely recognized, the therapies … the tide changed for sepsis with the …

… to be more qualified than cell transplantation in sepsis as a new therapeutic approach. …
and sepsis and therapeutic use of exosomes in bacterially mediated inflammation or sepsis. We …

… Although microbial products, such as endotoxins, have been targets for therapy in sepsis, a
… for hypotension and organ system dysfunction in sepsis, particularly since PAF is a potent …