[HTML][HTML] The molecular basis and therapeutic aspects of cisplatin resistance in oral squamous cell carcinoma

Y Cheng, S Li, L Gao, K Zhi, W Ren - Frontiers in oncology, 2021 - frontiersin.org
… the underlying mechanisms of cisplatin resistance in OSCC from the aspects of DNA damage
and … cisplatin resistance, which can provide new ideas to improve the clinical therapeutic

Cisplatin—Properties and clinical application

A Kopacz-Bednarska, T Król - Oncology in Clinical Practice, 2022 - journals.viamedica.pl
cisplatin, the development of cellular resistance, the range of side effects, and new possibilities
for using cisplatin in anticancer therapy… basic aspects of the adverse effect of cisplatin on …

Biochemical and molecular mechanisms of cisplatin resistance

ZH Siddik - … Relevant Resistance in Cancer Chemotherapy, 2002 - Springer
… who indicated that at least a 4-fold resistance can be acquired from the therapeutic use of …
The biochemical aspects of cisplatin resistance relate to drug accumulation, intracellular thiol …

[HTML][HTML] Cisplatin as an anti-tumor drug: cellular mechanisms of activity, drug resistance and induced side effects

AM Florea, D Büsselberg - Cancers, 2011 - mdpi.com
… Numerous mechanisms of cisplatin resistance were described … To minimize cisplatin resistance,
combinatorial therapies … The cellular and molecular aspects of the mechanism of action …

[HTML][HTML] Systems biology of cisplatin resistance: past, present and future

L Galluzzi, I Vitale, J Michels, C Brenner… - Cell death & …, 2014 - nature.com
… However, in the vast majority of cases, malignant cells exposed to cisplatin activate a … Thus,
a large fraction of cisplatin-treated patients is destined to experience therapeutic failure and …

[HTML][HTML] New advances into cisplatin resistance in head and neck squamous carcinoma: mechanisms and therapeutic aspects

H Hu, B Li, J Wang, Y Tan, M Xu, W Xu, H Lu - Biomedicine & …, 2023 - Elsevier
… expensive second-line therapies. Therefore, understanding … cisplatin resistance and to
identify more effective therapeutic … mechanisms underlying cisplatin resistance in HNSCC. This …

Therapeutic strategies to overcome cisplatin resistance in ovarian cancer

M Song, M Cui, K Liu - European journal of medicinal chemistry, 2022 - Elsevier
… of cisplatin resistance in ovarian cancer is systematically analyzed and summarized from the
aspects of … some inspiration for the treatment of cisplatin-resistance ovarian cancer. Image 1 …

[HTML][HTML] The challenging treatment of cisplatin-resistant tumors: State of the art and future perspectives

G Coffetti, M Moraschi, G Facchetti, I Rimoldi - Molecules, 2023 - mdpi.com
… cell membrane is the first step for cisplatin therapy to be successful. … aspect to evaluate, as
it could be useful in overcoming one of the primary issues involved in cisplatin resistance, ie, …

Cisplatin resistance in germ cell tumours: models and mechanisms

C Jacobsen, F Honecker - Andrology, 2015 - Wiley Online Library
… In conclusion, targeted therapy has up to now not proven to significantly improve the
outcome of patients with relapsed or … Has this aspect of malignant germ cells been studied? …

[HTML][HTML] Mitochondrial involvement in cisplatin resistance

V Cocetta, E Ragazzi, M Montopoli - International journal of molecular …, 2019 - mdpi.com
… of resistance phenomena, it still remains the only therapeutic option for several tumors.
Circumventing cisplatin resistanceresistance to chemotherapy, underlining a functional aspect of …