… lead to caspasemediated apoptosis, represent an attractive therapeutic target for the septic
… apoptotic pathways in sepsis syndrome and propose several potential therapeutic targets. …

… the development of sepsis if we are to optimize these present clinical therapies and/or develop
… last decade, emerging evidence in sepsis research suggests that apoptosis in a variety of …

… Thus manipulating apoptosis could be a new therapeutic approach in sepsis. Further,
exploring potential therapeutic targets related to apoptosis will be valuable in reversing …

… with sepsis syndrome will likely require multi-modal therapies … for septic patients at present,
further exploration of this clinical … with sepsis will require multiple therapeutic approaches, …

… therapy may offer a unique alternative sepsis treatment to shorten the apoptotic arm of sepsis,
revealing a number of targets within the apoptotic … /or adjuvant therapies that would have a …

… to explore their therapeutic … -apoptotic and anti-inflammatory effects by inhibiting IL-1β and
IL-18 release in the CLP rat model and showed significant therapeutic effects against sepsis (…

… Renewed exploration of the therapeutic utility of this pathway has focused on thrombomodulin,
… Probiotic treated subjects also exhibited levels of colonic epithelial apoptosis and cellular …

… Herein, we review the therapeutic … and modalities for sepsis, which is under
experimental … The accumulation of apoptotic cells is one of the major hallmarks of sepsis. …

… of apoptosis and inflammation, and their striking roles in sepsis … Further studies to explore
the mechanism by which cytosolic … delineating sepsis pathobiology and novel therapeutics …

… Much work has demonstrated that dysregulation of apoptosis does occur in … of sepsis. The
difficulty has been in tying the phenomenology of apoptosis into the pathophysiology of sepsis. …