The role and mechanism of pyroptosis and potential therapeutic targets in sepsis: a review
X Zheng, W Chen, F Gong, Y Chen, E Chen - Frontiers in immunology, 2021 - frontiersin.org
… from apoptosis. A growing number of studies have investigated pyroptosis and its relationship
with … targets of pyroptosis have been highlighted to explore their therapeutic effect and …
with … targets of pyroptosis have been highlighted to explore their therapeutic effect and …
Apoptosis and caspases regulate death and inflammation in sepsis
RS Hotchkiss, DW Nicholson - Nature Reviews Immunology, 2006 - nature.com
… It is possible however that the most effective therapy of sepsis might lie in targeting anti-apoptotic
therapy to specific cell populations. For example, it might be advantageous to …
therapy to specific cell populations. For example, it might be advantageous to …
Therapeutic potential of extracellular vesicles for sepsis treatment
… , anti-apoptotic, and immunomodulatory effects in sepsis models. The dual nature of EVs
in … One such new direction has been the exploration of cell-based therapeutics. Cell …
in … One such new direction has been the exploration of cell-based therapeutics. Cell …
Role of apoptotic cell death in sepsis
RS Hotchkiss, KW Tinsley, IE Karl - Scandinavian journal of …, 2003 - Taylor & Francis
… This new understanding of sepsis may lead to novel therapeutic approaches including …
Apoptosis in sepsis: a new target for therapeutic exploration. FASEB J 2001; 15: 879Á/92. …
Apoptosis in sepsis: a new target for therapeutic exploration. FASEB J 2001; 15: 879Á/92. …
Therapeutic potential of annexins in sepsis and COVID-19
… to apoptosis, are promising therapeutic agents to reduce the severity of inflammatory
processes in COVID-19. However, the exact mechanism of COVID-19 coagulopathy is not fully …
processes in COVID-19. However, the exact mechanism of COVID-19 coagulopathy is not fully …
The potential immunological mechanisms of sepsis
X Zhang, Y Zhang, S Yuan, J Zhang - Frontiers in Immunology, 2024 - frontiersin.org
… of sepsis. We also try to explore the future direction of sepsis diagnosis and therapy in …
Inhibition of lymphocyte apoptosis has been demonstrated to lower sepsis mortality (70). …
Inhibition of lymphocyte apoptosis has been demonstrated to lower sepsis mortality (70). …
Ferroptosis in sepsis: the mechanism, the role and the therapeutic potential
L Xl, Z Gy, CN - Frontiers in Immunology, 2022 - frontiersin.org
… non-apoptotic cell … sepsis can be confirmed and whether the exploration of ferroptosis as
a direction of intervention can bring a breakthrough in the treatment and management of sepsis …
a direction of intervention can bring a breakthrough in the treatment and management of sepsis …
Apoptosis-induced lymphopenia in sepsis and other severe injuries
T Girardot, T Rimmelé, F Venet, G Monneret - Apoptosis, 2017 - Springer
… Therapies modulating apoptosis represent an interesting approach to restore immune
competence … process in physiology and during severe injuries, we will explore the immunological …
competence … process in physiology and during severe injuries, we will explore the immunological …
Revisiting caspases in sepsis
… of apoptosis and inflammation, and their striking roles in sepsis … Further studies to explore
the mechanism by which cytosolic … delineating sepsis pathobiology and novel therapeutics …
the mechanism by which cytosolic … delineating sepsis pathobiology and novel therapeutics …
The pathogenesis and potential therapeutic targets in sepsis
W Zhang, H Jiang, G Wu, P Huang, H Wang, H An… - MedComm, 2023 - Wiley Online Library
… to abnormal lymphocyte apoptosis in mice during sepsis, … basis for further exploration of
the treatment of sepsis. Here, we … mechanisms of sepsis as well as therapeutic targets in the …
the treatment of sepsis. Here, we … mechanisms of sepsis as well as therapeutic targets in the …