[HTML][HTML] The therapeutic and prognostic implications of immunobiology in colorectal cancer: a review

AM Zaborowski, DC Winter, L Lynch - British Journal of Cancer, 2021 - nature.com
… unstable disease has important therapeutic and prognostic … colorectal cancer, novel
immunotherapies and the interaction of the immune system with each apex of the tripartite of cancer

[HTML][HTML] Immunogenomic classification of colorectal cancer and therapeutic implications

J Roelands, PJK Kuppen, L Vermeulen… - International journal of …, 2017 - mdpi.com
… The immune system has a substantial effect on colorectal cancer (CRC) progression. …
therapies) is influenced by the immune system. The molecular characterization of colorectal cancer

Therapeutic strategy in unresectable metastatic colorectal cancer

B Chibaudel, C Tournigand, T André… - Therapeutic …, 2012 - journals.sagepub.com
Colorectal cancer is the third most common cancer and the third cause of cancer death in
western countries [Globocan, 2008]. The main parameter to predict survival or relapse is tumor …

[HTML][HTML] The molecular characteristics of colorectal cancer: Implications for diagnosis and therapy

HT Nguyen, HQ Duong - Oncology letters, 2018 - spandidos-publications.com
… Despite improvements in early detection and treatment method in recent years, colorectal
cancer (CRC) remains the third most frequent and the fourth leading cause of cancer-…

[HTML][HTML] Recent advances in targeted therapy of colorectal cancer: impacts of monoclonal antibodies nanoconjugates

MA Khiavi, A Safary, MH Somi - BioImpacts: BI, 2019 - ncbi.nlm.nih.gov
… , the overall survival rate of cancer has not been improved. Colorectal cancer (CRC) is …
provided promising treatment modalities for effective therapy of cancer. The limitations of …

current management of metastatic colorectal cancer–the evolving impact of targeted drug therapies

T Yau, P Chan, Y Ching Chan… - Alimentary …, 2008 - Wiley Online Library
Background The field of colorectal cancer chemotherapy has been transformed by the advent
of molecule‐specific drugs. Combined use of such drugs enhances tumour response rates…

Targeted therapy of colorectal cancer

A Seeber, G Gastl - Oncology research and treatment, 2016 - karger.com
… -line therapy for metastatic colorectal cancer: NO16966 updated results. Br J Cancer 2011;…
plus bevacizumab in patients with metastatic colorectal cancer: a randomized phase III non-…

[HTML][HTML] Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies

SM Leto, L Trusolino - Journal of Molecular Medicine, 2014 - Springer
… with chemorefractory metastatic colorectal cancer experience … therapeutic resistance,
summarize research efforts aimed to improve patient selection, and present alternative therapeutic

[HTML][HTML] Diagnostic and therapeutic biomarkers in colorectal cancer: a review

JV de Assis, LA Coutinho, IT Oyeyemi… - … Journal of Cancer …, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is a public health concern and the second most common type of
cancer … This review provides an overview of recent advances in the search for colorectal cancer

Reactive oxygen species in colorectal cancer: The therapeutic impact and its potential roles in tumor progression via perturbation of cellular and physiological …

R Moradi‐Marjaneh, SM Hassanian… - Journal of cellular …, 2019 - Wiley Online Library
… signaling pathways that are involved in colorectal cancer (CRC) carcinogenesis. Although
… progression, diagnosis, and therapy with particular emphasis on ROS‐stimulated pathways. …