Vascular dysfunction in cerebrovascular disease: mechanisms and therapeutic intervention

AA Miller, K Budzyn, CG Sobey - Clinical science, 2010 - portlandpress.com
… However, gene therapy for the treatment of cerebrovascular disease is still in its infancy. To
date… of this therapeutic strategy for improving cerebrovascular endothelial function in disease. …

Oxidative stress in the pathogenesis of Alzheimer's disease and cerebrovascular disease with therapeutic implications

A Jurcau, A Simion - … (Formerly Current Drug Targets-CNS & …, 2020 - ingentaconnect.com
The significant gain in life expectancy led to an increase in the incidence and prevalence of
dementia. Although vascular risk factors have long and repeatedly been shown to increase …

[HTML][HTML] Vascular cognitive impairment: disease mechanisms and therapeutic implications

DA Levine, KM Langa - Neurotherapeutics, 2011 - Elsevier
… Mechanisms of Disease Shared mechanisms between cerebrovascular disease (CVD) and
… Vascular risk factors may lead to cerebrovascular dysfunction through pathways mediated …

A history of cerebrovascular disease

CE Storey, H Pols - Handbook of Clinical Neurology, 2009 - Elsevier
… Miller Fisher, with the recognition of the importance and the therapeutic implication of the
carotid … Therapeutic nihilism was replaced by an increasing armamentarium of therapeutic

Cerebrovascular disease is a major factor in the failure of elimination of Aβ from the aging human brain: implications for therapy of Alzheimer's disease

RO Weller, HY YOW, SD Preston… - Annals of the New …, 2002 - Wiley Online Library
… As age is a major risk factor for AD and for cerebrovascular disease (CVD), we test the
hypothesis that CVD inhibits the elimination of Aβ from the aging human brain. Sections from 100 …

The implication of haemorheologic abnormalities in cerebrovascular disease

E Ott, K Niederkorn, F Fazekas… - Clinical …, 1986 - content.iospress.com
… In a total of 101 healthy volunteers (58 males, 43 females) with a mean age of 52 years and
free of clinical signs due to cerebrovascular disease we demonstrated significantly altered …

Cerebrovascular consequences of hypertension: Therapeutic implications

JF Fazekas - The American Journal of Cardiology, 1966 - Elsevier
… such procedures, and to our inability to distinguish therapeutic from spontaneous improvement.
… It should, however, be conceded that operative intervention is undoubtedly the therapy of …

Sirtuins: possible clinical implications in cardio and cerebrovascular diseases

V Conti, M Forte, G Corbi, G Russomanno… - Current Drug …, 2017 - ingentaconnect.com
… and non-pharmacological therapies, cardio and cerebrovascular diseases are still a …
pathways involved in cardio and cerebrovascular diseases has highlighted the presence of …

Epidemiological findings on cerebrovascular diseases and their implications

DM Berkson, J Stamler - Journal of atherosclerosis research, 1965 - Elsevier
… the occurrence of cerebrovascular diseases in the United States, reviews the available
information relevant to problems of the causation of these diseases, and indicates implications of …

Lesions in cerebrovascular disease and their clinical implications.

EC Hutchinson - British Medical Journal, 1972 - ncbi.nlm.nih.gov
… to investigate" is generally less of a problem than "whom to investigate," and in this article
a practical approach will be adopted with a constant eye on possible therapeutic implications. …