Alzheimer's disease (AD) results from a series of dysfunctions which spread throughout the
cortex in a precise spatiotemporal manner, and which subsequently give rise to a
characteristic pattern of cognitive and non-cognitive symptoms. Whilst some of these
symptoms can be controlled with specific drug regimes, there are still no treatments
available to prevent the disease. Similarly, there are no drugs available which will reverse or
even halt the progression of the pathological changes which occur in the AD brain. It is …

Alzheimerdisease (AD), wasfirstrecognized in theearly1900'sbyAloisAlzheimer, a German
psychiatrist and neuro pathologist and named after him (Fig. 1). Auguste Deter, in 1902 is a
reported patient of Dr. Alois (Fig. 2). AD is the most common form of dementia affecting
millions of the geriatric population worldwide, mostly those above 65-85 yrs of age. Women
are more commonly affected than man [1]. Alzheimer currently afflicts about 5.2 million
Americans and withthe rapid escalationof theprevalence of thedisease, thefigureisexpected …