Alzheimer's disease pathogenesis and therapeutic interventions

MS Parihar, T Hemnani - Journal of clinical neuroscience, 2004 - Elsevier
… will also be complex and might require different interventions for treatment. Being multifactorial
pathogenicity of the disease, it is our opinion that a combined molecular, genetic and …

Alzheimer's disease: pathogenesis and therapeutic interventions

JO Ogbodo, CP Agbo, UO Njoku… - Current aging …, 2022 - ingentaconnect.com
Interventions: The pathogenesis of AD was extensively discussed in order to understand the
reasons for the interventions … of different therapeutic agents and approaches, gene therapy, …

Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions

A Abeysinghe, R Deshapriya, C Udawatte - Life sciences, 2020 - Elsevier
… are severely affected in AD, exact etiology is yet unknown. The β-… disease pathogenesis.
Currently there are five Food and Drug Administration (FDA) approved drugs as treatment

Pathogenesis of Alzheimer's disease

RH Swerdlow - Clinical interventions in aging, 2007 - Taylor & Francis
… Formulating a comprehensive AD pathogenesis theory capable … to formulate a comprehensive
AD pathogenesis theory. In doing so, … It was further argued “Alzheimer disease and senile …

Aβ-degrading enzymes: modulators of Alzheimer's disease pathogenesis and targets for therapeutic intervention

EA Eckman, CB Eckman - Biochemical Society Transactions, 2005 - portlandpress.com
… hallmark of all forms of AD (Alzheimer's disease) and reducing Aβ levels can prevent or …
disease. Aβ is produced continuously and its concentration is determined in part by the activities

Current progress, challenges and future prospects of diagnostic and therapeutic interventions in Alzheimer's disease

K Rajasekhar, T Govindaraju - RSC advances, 2018 - pubs.rsc.org
… The continuous and rapid rise in disease pathogenesis is … slow or prevent progression of
the disease. As a consequence, … AD pathogenesis is not understood owing to multiple disease

Molecular pathogenesis and interventional strategies for Alzheimer's disease: promises and pitfalls

S Bhute, D Sarmah, A Datta, P Rane… - ACS pharmacology & …, 2020 - ACS Publications
… most therapeutic interventions have … etiology and physiopathology, but none of the attempts
brought a convincing outcome. The present review attempts to address the novel therapeutic

Etiology and pathogenesis of late-onset Alzheimer's disease

BJ Balin, AP Hudson - Current allergy and asthma reports, 2014 - Springer
… more specific diagnosis of the disease process. In the discussions … research into disease
etiology and pathogenesis, and we … Alzheimer's Disease clinical and research update for health …

A review on Alzheimer's disease pathophysiology and its management: an update

A Kumar, A Singh - Pharmacological reports, 2015 - Elsevier
… The most likely expected treatment strategies includes γ- and β-secretase inhibitors, Aβ …
of AD pathogenesis and progression. We also summarize the existing therapeutic strategies till …

The role of mitochondrial dysfunction in Alzheimer's disease pathogenesis

T Ashleigh, RH Swerdlow, MF Beal - Alzheimer's & Dementia, 2023 - Wiley Online Library
… To promote new thinking of the pathogenesis of Alzheimer's disease (AD), we examine the
… the pathogenesis of AD is critical and needed for the development of effective therapeutics. …