[HTML][HTML] Macroautophagy and mitophagy in neurodegenerative disorders: Focus on therapeutic interventions

JD Magalhães, L Fão, R Vilaça, SM Cardoso, AC Rego - Biomedicines, 2021 - mdpi.com
… upregulated when blockage of macroautophagy occurs [8]. For the scope of this review,
macroautophagy and selective autophagy of mitochondria, known as mitophagy, will be further …

Myocardial autophagic energy stress responses—macroautophagy, mitophagy, and glycophagy

LMD Delbridge, KM Mellor… - American Journal of …, 2015 - journals.physiology.org
… Thus mitophagy, glycophagy, and macroautophagy regulatory pathways have become the
… for targeted therapeutic intervention. Chronically elevated macroautophagic activity in the …

Mitophagy and disease: new avenues for pharmacological intervention

R Taylor, SJ Goldman - Current pharmaceutical design, 2011 - ingentaconnect.com
mitophagy research, including background information on the history, mechanisms, and
regulation of macroautophagy… the role of mitophagy in both the development and treatment of …

Targeting autophagy and mitophagy for mitochondrial diseases treatment

M Villanueva Paz, D Cotán… - … on therapeutic …, 2016 - Taylor & Francis
… : macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA). In
macroautophagy, … This review specifically focuses on the role of macroautophagy in mitochondrial …

Mitophagy impairment in neurodegenerative diseases: Pathogenesis and therapeutic interventions

S Mani, G Swargiary, R Chadha - Mitochondrion, 2021 - Elsevier
… types of autophagy, macroautophagy has gained immense … In this current study, we review
the significance of mitophagy in … mitophagy in different NDDs and highlight recent therapeutic

Modulating autophagy and mitophagy as a promising therapeutic approach in neurodegenerative disorders

J Mishra, GK Bhatti, A Sehrawat, C Singh, A Singh… - Life sciences, 2022 - Elsevier
… So, targeting autophagy and mitophagy might be a potential therapeutic strategy for a …
Selective autophagy is the macroautophagy of a single cellular component, such as mitophagy for …

Autophagy: a target for therapeutic interventions in myocardial pathophysiology

A Halapas, A Armakolas… - … Opinion on Therapeutic …, 2008 - Taylor & Francis
… However, in hepatocytes there is evidence for a selective uptake of mitochondria by
macroautophagy (mitophagy), which is important for the removal of dysfunctional mitochondria …

[PDF][PDF] Mitophagy modulators

K Palikaras, A Princz… - … of Biomedical Gerontology, 2018 - tavernarakislab.gr
… characterized so far: macroautophagy (hereafter referred to … ; mitophagy belongs to the first
category, macroautophagy. … still indicates the therapeutic potential of this mitophagy receptor. …

[HTML][HTML] Mitophagy in human diseases

L Doblado, C Lueck, C Rey, AK Samhan-Arias… - International journal of …, 2021 - mdpi.com
macroautophagy pathways are often dispensable for selective autophagy [8]. Therefore,
mitophagy … suggest that inhibition of mitophagy can also be of therapeutic benefit; for example, it …

The interplay between selective types of (macro) autophagy: Mitophagy and xenophagy

T Rubio-Tomás, A Sotiriou, N Tavernarakis - International Review of Cell …, 2023 - Elsevier
… With respect to anti-cancer therapies, pharmacological modifiers of autophagy or mitophagy
have been considered as a treatment for cancer. In addition, research using these drugs …