Challenges and new opportunities in the investigation of new drug therapies to treat frontotemporal dementia
ED Huey, N Armstrong, P Momeni… - … opinion on therapeutic …, 2008 - Taylor & Francis
… of drug therapies for frontotemporal dementia spectrum … of frontotemporal dementia spectrum
disorders; second, a discussion of the challenges in the development of drug therapies third…
disorders; second, a discussion of the challenges in the development of drug therapies third…
[HTML][HTML] New insights and therapeutic opportunities for progranulin-deficient frontotemporal dementia
S Amin, G Carling, L Gan - Current Opinion in Neurobiology, 2022 - Elsevier
… Frontotemporal dementia (FTD) is the second most common form of dementia. It affects the
frontal … We also review the opportunities and challenges toward developing therapies and …
frontal … We also review the opportunities and challenges toward developing therapies and …
Advances in treatment of frontotemporal dementia
N Magrath Guimet… - The Journal of …, 2022 - Am Neuropsych Assoc
… a behavioral therapy called “routinizing therapy”—in which stimulus-bound and stereotypic
behaviors are replaced with appropriate behaviors—improved. This therapy was reported to …
behaviors are replaced with appropriate behaviors—improved. This therapy was reported to …
Therapeutic trial design for frontotemporal dementia and related disorders
… The frontotemporal dementia (FTD) spectrum is a heterogeneous group of neurodegenerative
syndromes with overlapping clinical, molecular and pathological features, all of which …
syndromes with overlapping clinical, molecular and pathological features, all of which …
Advances and controversies in frontotemporal dementia: diagnosis, biomarkers, and therapeutic considerations
… frontotemporal lobar degeneration. This Review will use the term frontotemporal dementia
when focusing on the clinical syndromes of behavioural variant of frontotemporal dementia …
when focusing on the clinical syndromes of behavioural variant of frontotemporal dementia …
New directions for frontotemporal dementia drug discovery
JQ Trojanowski, K Duff, H Fillit… - … & Dementia, 2008 - Wiley Online Library
… by TDP-43 proteinopathy will benefit from neuroprotective therapies in the absence of clear
… therapeutic strategies that could benefit both tauopathies and TDP-43 proteinopathies. …
… therapeutic strategies that could benefit both tauopathies and TDP-43 proteinopathies. …
Approaches to develop therapeutics to treat frontotemporal dementia
LP Elia, T Reisine, A Alijagic, S Finkbeiner - Neuropharmacology, 2020 - Elsevier
… Frontotemporal dementia is the second prevalent dementia after Alzheimer's disease. …
Efforts to raise PGRN levels are a therapeutic strategy for frontotemporal dementia. …
Efforts to raise PGRN levels are a therapeutic strategy for frontotemporal dementia. …
Management of frontotemporal dementia: targeting symptom management in such a heterogeneous disease requires a wide range of therapeutic options
… therapies for the management of frontotemporal dementia (FTD)… Progress in obtaining approval
and therapeutic indications for … and publications investigating therapeutic options in FTD, …
and therapeutic indications for … and publications investigating therapeutic options in FTD, …
New routes in frontotemporal dementia drug discovery
… Introduction: Research into the pathogenic mechanisms behind frontotemporal dementia
(FTD) has yielded several new targets for therapeutic intervention; such targets include specific …
(FTD) has yielded several new targets for therapeutic intervention; such targets include specific …
Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs
… Frontotemporal dementia (FTD) is a heterogeneous clinical entity that includes several
disorders characterized by different cellular mechanisms, involving different brain regions, with …
disorders characterized by different cellular mechanisms, involving different brain regions, with …
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